pachyonychia congenita/hyperalgesia

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Chronic pain in pachyonychia congenita: evidence for neuropathic origin.

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BACKGROUND Pachyonychia congenita (PC) is a rare autosomal dominant skin disease, with chronic pain being the most prominent complaint. Histological studies showing alterations in sensory innervation, along with reports on alterations in mechanical sensitivity, suggest that PC may be a form of

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