paraproteinemias/edema

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Use of SEPs to localize degeneration in a rare polyneuropathy: studies on polyneuropathy associated with pigmentation, hypertrichosis, edema, and plasma cell dyscrasia.

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Peripheral and cental nerve conduction were studied in five patients who had polyneuropathy associated with pigmentation, hypertrichosis, edema, and plasma cell dyscrasia by using the short-latency somatosensory evoked potential (SEP) to electrical stimulation of the median nerve at the wrist. The

[Clarkson syndrome: a rare clinical condition characterized by generalized edema associated to monoclonal gammopathy].

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Generalized edema is commonly due to cardiac failure, renal changes, hepatic and metabolic disturbances, or it can be idiopathic, i.e. primitive lymphedema. Here we describe a patient with several episodes of fluid extravasation characterized by hypotension, hemoconcentration and functional renal

[Endoneurial deposition of immunoglobulins in cases of plasma cell dyscrasia associated with polyneuropathy, edema and pigmentation (author's transl)].

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[A case of secondary C1 inhibitor deficiency associated with benign monoclonal gammopathy and angioneurotic edema (author's transl)].

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Accelerated conversion of androgen to estrogen in plasma-cell dyscrasia associated with polyneuropathy, anasarca, and skin pigmentation.

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[Lower limb edema and monoclonal gammopathy in a 74-year-old man].

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[TAFRO syndrome and monoclonal gammapathy: Uncommon association!].

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Castleman's disease is a lymphoproliferative disorder characterized by angiofollicular lymph node hyperplasia. Recently, a new variant of multicentric Castleman's disease has been identified in Japan called TAFRO syndrome. It is characterized by a constellation of symptoms: thrombocytopenia,

Bilateral non-simultaneous optic neuropathy and unilateral macular edema in a patient with POEMS syndrome.

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OBJECTIVE To report a case of bilateral non-simultaneous optic neuropathy and unilateral macular edema in a patient with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome. METHODS A 61-year-old man with POEMS syndrome had bilateral anterior optic

[Chronic edema, monoclonal dysglobulinemia and profuse telangiectasia: a distinct entity?].

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BACKGROUND Monoclonal gammopathy and edema are features encountered during several diseases, especially systemic capillary leak syndrome. The diagnoses of POEMS syndrome, edematous systemic scleroderma and a fortuitous association may be also discussed. We report the cases of two patients which did

A case of crystalline keratopathy in monoclonal gammopathy of undetermined significance (MGUS).

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A 62-year-old female visited our clinic with progressively decreased vision in both eyes beginning 12 years prior. Idiopathic corneal opacity in all layers of the cornea was found in both eyes. One year later, we performed penetrating keratoplasty on the undiagnosed right eye. During post-surgical

Light chain deposition disease developing 15 years following the diagnosis of monoclonal gammopathy of undetermined significance.

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A 64-year-old woman was admitted because of leg edema. Fifteen years previously she had been diagnosed with monoclonal gammopathy of undetermined significance (MGUS). Urinary immunoelectrophoresis demonstrated positivity for IgA kappa light chains. Bone marrow aspiration revealed a mild

Necrobiotic xanthogranuloma without a monoclonal gammopathy.

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Necrobiotic xanthogranuloma (NXG) is an indolent non-Langerhans cell histiocytosis characterized by yellow xanthomatous plaques that tend to ulcerate. Necrobiotic xanthogranulomas have a predilection for the bilateral periorbital region and often present with consequential ophthalmic findings.

Anti-neurofilament antibodies in neuropathy with monoclonal gammopathy of undetermined significance produce experimental motor nerve conduction block.

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Elevated levels of serum antibodies to neurofilament proteins have been associated with a variety of neurological diseases, including autoimmune disorders such as neuropathy with monoclonal gammopathy of undetermined significance (MGUS). The pathological significance of anti-neurofilament antibodies

Plasma-cell dyscrasia with polyneuropathy. The spectrum of POEMS syndrome.

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BACKGROUND The POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome and osteosclerotic myeloma (polyneuropathy and sclerotic bone lesions) may both be manifestations of plasma-cell dyscrasia, but the interrelation of these diseases is not clear. We

Kennedy Disease Misdiagnosed as Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes (POEMS) Syndrome: A Case Report.

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OBJECTIVE The aim of this paper was to report the first case of Kennedy disease misdiagnosed as polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome. METHODS A 58-year-old Chinese man presented with limb numbness, progressive limb proximal weakness,

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