pelizaeus-merzbacher disease/nicotine

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Testicular changes due to graded doses of nicotine in albino mice.

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Administration of graded doses of nicotine (0.2 mg, 0.4 mg and 0.6 mg/100 g body weight) for 15 days to the adult mice reduced the weight of testis, number of spermatocytes and spermatids, but increased the number of spermatogonia which may be due to reduced conversion to subsequent stages. There is

Tobacco smoking protective effect via remote ischemic preconditioning on myocardial damage after elective percutaneous coronary intervention: Subanalysis of a randomized controlled trial.

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Remote ischemic preconditioning (RIPC) is promising for preventing periprocedural myocardial damage (pMD) in patients undergoing percutaneous coronary intervention (PCI). However, the impact of RIPC on pMD on smokers is not well elucidated. The aim of this study was to investigate an

Stress exposure and the risk for the onset of alcohol use disorders and nicotine dependence in deployed military personnel: the role of prior internalizing disorders.

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OBJECTIVE This prospective study aimed to investigate whether prior internalizing disorders (PIDs) moderate the relationship between stress exposure (SE) and the onset of alcohol use disorders (AUDs) and nicotine dependence (ND) in deployed military personnel. METHODS 358 male soldiers were examined

Prevalence of most commonly reported tobacco-associated lesions in central Gujarat: A hospital-based cross-sectional study.

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BACKGROUND Oral cancer is a major health problem in tobacco users worldwide and is one of the ten most common cancers. India alone accounts for 1/3 rd of the world's oral cancer and has a high rate of potentially malignant disorders (PMDs). The most common predisposing factors are smoking, smokeless

Evaluation of Health Risk Level of Hand-Arm and Whole-Body Vibrations on the Technical Operators and Equipment in a Tobacco-Producing Company in Nigeria.

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Vibration is experienced when a body is subjected to either internal or external forces which cause oscillation, with most operators of industrial equipment often exposed to high dosage, higher than the stipulated values. In this research, Digital Real-Time Frequency Analyzer (RSA 5106A) was used,

Oral submucous fibrosis in a 5 year old child

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Oral submucous fibrosis (OSMF) is one of the potentially malignant disorders (PMDs), predominantly observed in adults with a habit of chewing areca nut. A rapid increase in the use of commercially available nicotine products, especially among the children and adolescents, is a reason for

Actinic cheilosis: early intervention prevents malignant transformation.

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Potentially malignant disorders (PMD) have a high risk of malignant transformation. Habits such as tobacco and alcohol use predispose to PMD and subsequently to an oral carcinoma. Oral squamous cell carcinoma (OSCC) can occur even without the usage of tobacco. Occupational exposure to actinic rays

Prevalence of oral potentially malignant disorders in workers of Udupi taluk.

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OBJECTIVE The objective was to assess the prevalence and risk factors of oral potentially malignant disorders (PMD) among industrial workers of Udupi taluk, Karnataka. METHODS The sample consisted of industrial workers aged >18 years from randomly selected industries in Udupi Taluk. A

Investigation of viral etiology in potentially malignant disorders and oral squamous cell carcinomas in non-smoking, non-drinking patients.

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Head and neck squamous cell carcinomas (HNSCC) are the seventh most frequent cancers. Among HNSCCs, oral squamous cell carcinomas (OSCCs) include several anatomical locations of the oral cavity, but exclude the oropharynx. The known risk factors for OSCCs are mainly alcohol consumption and tobacco

DNA aneuploidy and dysplasia in oral potentially malignant disorders: association with cigarette smoking and site.

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To date there are still no reliable biomarkers for oral potentially malignant disorders (PMDs) to predict the risk of progression to squamous cell carcinoma (SCC). Within a prospective clinical trial of patients with PMDs, DNA content flow cytometry (DNA FCM) was evaluated for 60 PMDs using fresh

Utility of DNA-Specific Stains in Micronuclei Assay as a Marker of Genotoxicity in Oral Potentially Malignant Disorders and Oral Squamous Cell Carcinoma.

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The term oral potentially malignant disorder (OPMD) was recommended to refer to precancer as it conveys that not all disorders described under this term may transform into cancer. Oral squamous cell carcinoma (OSCC) arises through an accumulation of genetic alterations, deoxy

Influence of risk factors on patients suffering from potentially malignant disorders and oral cancer: A case-control study.

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UNASSIGNED Tobacco use can alone lead to death worldwide, especially in developing and underdeveloped countries. China and Brazil are the world's largest producer of tobacco. India holds the third place in producing, and it is the fourth largest consumer of tobacco and its products in the

Status of salivary lipid peroxidation in oral cancer and precancer.

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BACKGROUND Lipid oxidation gives rise to number of secondary by-products. Malondialdehyde (MDA) is the principal and most widely studied product of polyunsaturated fatty acid peroxidation. This aldehyde is a highly toxic molecule and should be considered as more than just a marker of lipid

Survival study of leukoplakia malignant transformation in a region of northern Spain.

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BACKGROUND Oral leukoplakia is the most common potentially malignant disorder (PMD) of the oral cavity. The objectives of this study are to determine the clinicopathologic features in a group of patients with oral leukoplakia of Northern Spain (Galicia), determining the factors associated to

Analysis of various risk factors affecting potentially malignant disorders and oral cancer patients of Central India.

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BACKGROUND The use of tobacco/betel quid can alone lead to death. India is the fourth largest consumer of tobacco/betel quid in the world and the third-largest producer of tobacco/betel quid after China and Brazil. OBJECTIVE A case-control study was carried out to assess the prevalence and various

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