peri-implantitis/protease

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Bacterial profiles and proteolytic activity in peri-implantitis versus healthy sites.

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Peri-implantitis is a biofilm-induced destructive inflammatory process that, over time, results in loss of supporting bone around an osseointegrated dental implant. Biofilms at peri-implantitis sites have been reported to be dominated by Gram-negative anaerobic rods with a proteolytic metabolism

In vivo expression of proteases and protease inhibitor, a serpin, by periodontal pathogens at teeth and implants.

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Porphyromonas gingivalis and Tannerella forsythia secrete proteases, gingipains and KLIKK-proteases. In addition, T. forsythia produces a serpin (miropin) with broad inhibitory spectrum. The aim of this pilot study was to determine the level of expression of miropin and individual proteases in vivo

Effect of conventional and contemporary disinfectant techniques on three peri-implantitis associated microbiotas.

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OBJECTIVE To evaluate the antiseptic properties of five different disinfectant techniques on three different peri-implantitis (PI) associated biofilms. METHODS 90 implant titanium disks, with the same thickness and diameter, were prepared and randomly divided into 18 groups (n = 5) based on the

Peri-implant diseases and host inflammatory response involving mast cells: a review.

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Mast cells (MCs) are motile granule-containing cells that originate from bone marrow pluripotential haematopoietic cells, circulate in blood and extravasate in tissues where they play an important role in inflammation, host defense and tissue repair. We herein review the English literature over the

Establishment of Epithelial Attachment on Titanium Surface Coated with Platelet Activating Peptide.

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The aim of this study was to produce epithelial attachment on a typical implant abutment surface of smooth titanium. A challenging complication that hinders the success of dental implants is peri-implantitis. A common cause of peri-implantitis may results from the lack of epithelial sealing at the

Function of Platelet-Induced Epithelial Attachment at Titanium Surfaces Inhibits Microbial Colonization.

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The aim of this study was to evaluate the barrier function of platelet-induced epithelial sheets on titanium surfaces. The lack of functional peri-implant epithelial sealing with basal lamina (BL) attachment at the interface of the implant and the adjacent epithelium allows for bacterial invasion,

Content of urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 in oral mucosa and inflamed periodontal tissue.

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OBJECTIVE Recent literature has demonstrated that local proteolytic enzymes participate in periodontitis and peri-implantitis. The aim of the present study was to evaluate whether the serine proteases urokinase-type plasminogen activator (uPA) and its plasminogen activator inhibitor type 1 (PAI-1)

Anti-inflammatory and macrophage polarization effects of Cranberry Proanthocyanidins (PACs) for periodontal and peri-implant disease therapy

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Background and objective: Macrophages' cytokine expression and polarization play a substantial role in the host's "destructive" inflammatory response to periodontal and peri-implant pathogens. This study aimed to evaluate cell viability,

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