phosphatidyl choline/edema

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A study of ozone-induced edema in the isolated rat lung in relation to arachidonic acid metabolism, mixed-function oxidases and angiotensin converting enzyme activities.

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In order to elucidate the role of arachidonic acid in the pathogenesis of ozone-induced pulmonary edema, isolated rat lungs were exposed to 14C-arachidonic acid in the presence or absence of ozone and the incorporation of radiolabelled arachidonate into pulmonary cell lipids was studied. The

Complexation with phosphatidyl choline as a strategy for absorption enhancement of boswellic acid.

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Boswellic acids (BAs) are isolated from oleo gum resin of Boswellia serrata and are reported to be effective as anti-inflammatory, hypolipidemic, immunomodulatory, and anti-tumor. Pharmacokinetic studies of boswellic acid reveal its poor absorption through the intestine. The objective of the present

A human ciliopathy with polycystic ovarian syndrome and multiple subcutaneous cysts: A rare case report.

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Ciliopathies is a group of clinically and genetically overlapping disorders due to cilia abnormalities and multiple organ systems are involved in.We present a young female patient who showed renal function impairment, Caroli syndrome (CS), liver cirrhosis,

Characterization and cloning of a novel phospholipase A(2) from the venom of Trimeresurus jerdonii snake.

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A phospholipase A(2) (PLA(2)), called jerdoxin, was isolated from Trimeresurus jerdonni snake venom and partially characterized. The protein was purified by three chromatographic steps. SDS-polyacrylamide gel electrophoresis in the presence or absence of dithiothreitol showed that it had a molecular

[Experimental study of glucocorticoid in the treatment of acute respiratory distress syndrome induced by E.coli].

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OBJECTIVE To evaluate the effect of glucocorticoid (GC) in the treatment of septic acute respiratory distress syndrome (ARDS). METHODS ARDS model was reproduced by intraperitoneal injection of E.coli in piglets. Nine male piglets were randomly divided into control (C group), early (GC1) and middle

Traumatic head injury and pulmonary damage.

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Head-injury victims may develop pulmonary complications such as hemorrhagic edema, congestion, and hyperemia. In the present experiments we examined changes in lung surface tension, cholesterol, and phospholipids of alveolar lavage recovered from cats experimentally exposed to a sudden lethal blow

Surfactant alterations following acute bleomycin and hyperoxia-induced lung damage.

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Hamsters treated with 0.5 U/kg intratracheal bleomycin and exposed for 24 h to 80% O2 develop acute respiratory failure 72 h after treatment. To examine indirectly the lung epithelial type II cell changes, alterations in pulmonary surfactant was measured. Presence and amount of dipalmitoyl

Acceleration of epithelial cell syndecan-1 shedding by anthrax hemolytic virulence factors.

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BACKGROUND It has been recently reported that major pathogens Staphylococcus aureus and Pseudomonas aeruginosa accelerate a normal process of cell surface syndecan-1 (Synd1) ectodomain shedding as a mechanism of host damage due to the production of shedding-inducing virulence factors. We tested if

Pharmacodynamic and pharmacokinetic evaluation of lipid microspheres of indomethacin.

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Lipid microspheres (LM) of indomethacin were prepared using phosphatidyl choline and soya bean oil. LM of required size (< 1 micron) were obtained by intermittent microscopic observation while homogenization. Anti-inflammatory activity of lipo-indomethacin was compared with free indomethacin by

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