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phospholipase/necrosis
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7 results
Phospholipase A2 inhibitors as mediators of gene expression
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the fields of radiation biology and cell biology. More particularly, it concerns the attenuation of the effect of ionizing radiation induced activation of tumor necrosis factor by inhibitors of
Phospholipase A2 inhibitors as mediators of gene expression
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the fields of radiation biology and cell biology. More particularly, it concerns the attenuation of the effect of ionizing radiation induced activation of tumor necrosis factor by inhibitors of
Treatment of tumors
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FIELD OF THE INVENTION
This invention relates to treatment of mammals, including humans suffering from cancerous tumors, particularly malignant gliomas and other tumors of the central nervous system, and to tumor models for evaluating effectiveness of such treatments.
BACKGROUND OF THE INVENTION
In
Antigen-binding fusion proteins
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the production of antigen-binding fusion molecules. More specifically, the invention relates to fusion forms of antigen-binding proteins having an immunoeffector moiety and/or a cytolytic moiety,
Antigen-binding fusion proteins
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the production of antigen-binding fusion molecules. More specifically, the invention relates to fusion forms of antigen-binding proteins having an immunoeffector moiety and/or a cytolytic moiety,
Regulation of x-ray mediated gene expression
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the fields of radiation biology and cell biology. More particularly, it concerns the attenuation of the effect of ionizing radiation induced activation of cytokines, such as tumor necrosis factor, by
Use of chemical compounds that can inhibit the toxic activity of sphingomyelinase D from venoms of Loxosceles spiders and pharmaceutical composition comprising said compounds
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FIELD OF THE INVENTION
The present invention relates to the use of chemical compounds capable of inhibiting the toxicity of sphingomyelinase D of the venom of spider Loxosceles. More specifically, the instant invention relates to the use of benzenesulfonamides and benzenesuphonates on toxicity
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