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Cannabis for Acute Migraine: a Randomized, Double-blind, Placebo-controlled, Crossover Trial

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In this double-blind, randomized, crossover trial, subjects will treat 4 separate migraine attacks with 4 different treatments. Inhaled cannabis will be administered using a portable vaporization system (Mighty Medic; Storz & Bickel) based on a validated Storz & Bickel system and using a

The Effect of Intravenous Fluid Therapy in Acute Migraine Attacks

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Introduction Headache is a common complaint that is seen in 70-80% of the population and is a common health problem in emergency services. When evaluating the patient with headache, the first step is to determine whether the headache is primary or secondary (1, 2). Primary headaches are classified

Efficacy and Safety of Nerivio Device for Acute Treatment of Migraine in People With Chronic Migraine

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This open label study includes up to four visits. The enrollment and application training may occur in two separate visits instead of one. First visit - The first visit will include screening, enrollment and training on the application. Enrollment: The screening process will include an eligibility

Transnasal Therapy for Acute Migraine Attack

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Migraine headaches are associated with significant impairment of quality of life and loss of productivity. High-flow oxygen has been successfully used in several clinical trials and vasoconstriction of blood vessels has been postulated as a possible mechanism. Some researchers have suggested that

Safety and Efficacy of Nerivio™ for the Acute Treatment of Migraine in Adolescents

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This open label study includes 3 phases and up to 4 visits. All visits will be conducted in the presence of a parent/guardian. First visit - enrollment: The first visit will include screening, enrollment and training on the application in diary mode. The screening process will include an eligibility

Effects of Lifestyle Modification on Vestibular Migraine

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Significance Dizziness is a frequently reported symptom encountered by healthcare providers, affecting 20-30% of the general population [9, 10]. Vestibular migraine (VM) is one of the more common causes of dizziness, including rotational vertigo, and is reported to be the diagnosis in 11.4% of

Intrathecal Atropine vs IV Metoclopramide for Nausea & Vomiting During CS

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Patients After obtaining the approval of the Mansoura Faculty of Medicine Institutional Research Board (MFM-IRB) and registration with ClinicalTrials.gov, this prospective double blind randomized study will be conducted in the next 6 months on 100 pregnant women undergoing elective CS in obstetric

Valproic Acid and Dihydroergotamine as Abortive Therapy in Pediatric Migraine

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The purpose of this study is to compare valproic acid (VPA) and dihydroergotamine (DHE) alone and sequentially in the treatment of pediatric migraines. Inpatient pediatric migraine patients (based on International Classification of Headache Disorders, ICHD-II criteria) or those admitted to the

Autologous Plasma Treatment for Severe Dry Eye Patients

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Dry eye is a multi-factorial disease that is frequently encountered in ophthalmological practice. Common dry eye symptoms include eye irritation, heaviness of the eyelids, blurred vision and light sensitivity. The worldwide prevalence of dry eye is generally high. In Asia, dry eye may affect up to

rTMS Treatment of Persistent Headache and Post Concussion Symptoms Attributed to Mild Traumatic Injury to the Head

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Demographic information will be collected two weeks prior to starting the study including age, sex, education, headache history, concussion history, past medical history, medication use, and family medical history. Headache history will be collected including frequency, severity, medication-use,

Intranasal Lidocaine to Treat Pediatric Migraine in the Emergency Department

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This will be a double-blinded, randomized-controlled trial using intranasal lidocaine to provide fast-acting pain relief in pediatric patients presenting with migraine to an urban pediatric emergency department (ED). Typically, abortive therapy for migraine in many emergency departments begins with

RCT of SPG Blocks for Post-dural Headache

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The postdural puncture headache (PDPH) is a well-documented complication of dural puncture. Depending on a number of factors, the overall incidence of PDPH following unintended dural puncture with an epidural placement needle is typically around 50%, but can be as high as 70% for certain

Evaluation of a Novel Device for Treatment of Migraine Headache

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Nerivio Migra is intended for the acute treatment of migraine with or without aura in patients 18 years of age or older. It is self-applied to the upper arm. Treatments are self-administered by the user at the onset of a migraine attack. The device delivers extra cephalic transcutaneous electrical

Migraine Prevention Using ActiPatch

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Migraine is a common neurological disorder characterized by episodes of unilateral or bilateral headache lasting for hours to days, which may be accompanied by photophobia, phonophobia, nausea and vomiting. Pharmacological management is the first treatment option for subjects with migraine. However,

The Occurrence of Post Dural Puncture Headache After Epidural Blood Patch

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Currently, spinal anesthesia is commonly used for cesarean section in many institutes, since it is a safe technique for both mother and child, with high satisfaction of obstetricians and their colleagues. Bloom, et al. claimed that there was 37,142 women underwent cesarean section in 2002 where 94%

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