phthalic acid/seizures

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Inhibition of brain glutamate decarboxylase by 4,5-dihydroxyisophthalic acid and related compounds.

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Hydroxybenzoic and phthalic acids and their related compounds were tested for inhibitory activity to brain glutamate decarboxylase. Of mono-, di-, and trihydroxybenzoic acids, gallic acid was the most inhibitory, giving 50% inhibition at a concentration of 0.17 mM. Dihydroxybenzoic acids were less

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