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polyamine/inflammation

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11 results

Methods and bicyclic polyamine compositions for the treatment of inflammation

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BACKGROUND OF THE INVENTION RELATED APPLICATIONS The active agents employed in the methods and compositions of the invention, as well as methods for their preparation, are described in U.S. patent application Ser. No. 08/080,692 filed Jun. 22, 1993, the entire contents and disclosures of this

Augmenting moieties for anti-inflammatory compounds

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FIELD OF THE INVENTION The invention is directed to anti-inflammatory compounds which are synergistically enhanced in their anti-inflammatory activity through conjugation with specific amino acids and/or with specific other anti-inflammatory components. Also disclosed are methods of increasing the

Proteoglycan compositions for treating prostate and bladder inflammatory conditions

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BACKGROUND OF THE INVENTION The invention is generally related to the treatment of inflammatory conditions. More specifically, the invention is related to compositions containing inhibitors of mast cell activation and secretion such as a proteoglyean that are designed to be used as dietary

Proteoglycan compositions for treatment of cardiovascular inflammatory diseases

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BACKGROUND OF THE INVENTION The invention is generally related to the treatment of inflammatory conditions. More specifically, the invention is related to compositions containing inhibitors of mast cell activation and secretion such as a proteoglycan that are designed to be used as dietary

Proteoglycan compositions for treating arthritic inflammatory conditions

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BACKGROUND OF THE INVENTION The invention is generally related to the treatment of inflammatory conditions. More specifically, the invention is related to compositions containing inhibitors of mast cell activation and secretion such as a proteoglycan that are designed to be used as dietary

Proteoglycan compositions for treating arthritic inflammatory conditions

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BACKGROUND OF THE INVENTION The invention is generally related to the treatment of inflammatory conditions. More specifically, the invention is related to compositions containing inhibitors of mast cell activation and secretion such as a proteoglycan that are designed to be used as dietary

Copper chelators for treating ocular inflammation

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FIELD OF THE INVENTION In one aspect, the present invention relates to therapeutic uses of organic compounds, including nitrogen-containing compounds such as polyamines, as well as therapeutic compositions containing such compounds, such as ophthalmological medicaments. BACKGROUND OF THE

Anti-inflammatory compositions for treating multiple sclerosis

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BACKGROUND OF THE INVENTION The invention is generally related to the treatment of inflammatory conditions. More specifically, the invention is related to compositions containing inhibitors of mast cell activation and secretion such as a proteoglycan and a flavonoid compound that are designed to be

Methods of treating chronic inflammatory diseases using carbonyl trapping agents

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to the clinical treatment of chronic inflammatory disorders. For purposes of this invention, the category of chronic inflammatory disorders includes chronic gingivitis, chronic periodontitis, chronic autoimmune gastritis,

Polyamine compounds for treating chemokine receptor mediated diseases

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BACKGROUND Chemokines are a family of cytokines that regulate the adhesion and transendothelial migration of leukocytes during an immune or inflammatory reaction (Mackay C. R., Nat. Immunol., (2001) 2:95; Olson et al., Am. J. Physiol. Regul. Integr. Comp. Physiol., (2002) 283:R7). Chemokines also

Composition for treating hormonally-dependent cancers

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BACKGROUND OF THE INVENTION The invention is generally related to the treatment of inflammatory conditions. More specifically, the invention is related to compositions containing inhibitors of mast cell activation and secretion such as a proteoglycan that are designed to be used as dietary
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