polycythemia/albumin

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Can ischemia-modified albumin be a valuable indicator of tissue ischemia in polycythemia vera?

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The red cell expansion in polycythemia vera (PV) causes hyperviscosity affecting blood flow, which plays a major role in the pathogenesis of both microcirculatory disturbances and ultimately thromboses. Ischemia-modified albumin (IMA) is produced during an ischemic states and is present in blood in

Post-renal transplant erythrocytosis.

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Erythrocytosis is a relatively common phenomenon following renal transplantation. It is not only associated with some special clinical conditions, but also increases the risk of thromboembolism. We therefore studied the clinical manifestations and possible risk factors of erythrocytosis in our

Stimulus-specific defect in oxidative metabolism of polymorphonuclear granulocytes in polycythemia vera.

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We investigated polymorphonuclear granulocyte (PMN) function in polycythemia vera (PV) in relation to healthy controls. PMN oxidative metabolism, assessed by chemiluminescence (CL), was significantly lower in PV patients after stimulation with leukotriene B4 (LTB4) and f-Met-Leu Phe (fMLP) (60% of

Cell separation, cell differential and granulocyte colony frequency in polycythemia vera.

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In seven patients with polycythemia vera, the agar colony growth of bone marrow total nucleated cell suspensions and of the cell fractions obtained with an albumin discontinuous density gradient were studied. In one patient, the density distribution of colony-forming units in culture (CFUc) before

Analysis of red cell mass and plasma volume in patients with polycythemia.

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BACKGROUND Polycythemia describes an increased proportion of red blood cells in the peripheral blood. In absolute polycythemia, there is increased red cell mass (RCM) with normal plasma volume, in contrast with apparent polycythemia, in which there is increased or normal RCM and decreased plasma

An unusual cause of hypercalcemia in polycythemia vera: parathyroid adenoma.

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In this paper we describe a patient with polycythemia vera (PV), who presented with hypercalcemia due to a parathyroid adenoma. In November 1999, the patient was admitted to our hospital with meteorism and constipation. Her physical examination revealed plethora and hepatosplenomegaly. Laboratory

Red cell mass and plasma volume measurements in polycythemia: evaluation of performance and practical utility.

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BACKGROUND Despite the absence of any systematic evidence for diagnostic utility, red cell mass (RCM) measurement has been endorsed as a major diagnostic criterion for polycythemia vera (PV) based on a set of eligibility criteria for a clinical trial formulated by an International PV Study Group in

Histopathological manifestations of membranoproliferative glomerulonephritis and glomerular expression of plasmalemmal vesicle-associated protein-1 in a patient with polycythemia vera.

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Only a few cases of various glomerulonephropathies have been reported in patients with polycythemia vera. We report the case of a 72-year-old female with polycythemia vera in whom renal biopsy examination showed membranoproliferative glomerulonephritis (MPGN)-like lesion and glomerular expression of

Global REACH 2018: High Blood Viscosity and Hemoglobin Concentration Contribute to Reduced Flow-Mediated Dilation in High-Altitude Excessive Erythrocytosis

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Excessive erythrocytosis (EE; hemoglobin concentration [Hb] ≥21 g/dL in adult males) is associated with increased cardiovascular risk in highlander Andeans. We sought to quantify shear stress and assess endothelial function via flow-mediated dilation (FMD) in male Andeans with and without EE. We

Glycated albumin level during late pregnancy as a predictive factor for neonatal outcomes of women with diabetes.

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OBJECTIVE To investigate the association between glycated albumin (GA) in diabetic mothers and complications in their children, and to determine GA cutoff values for predicting complications in infants. METHODS This hospital-based case-control study involved 71 Japanese diabetic mothers and their

RBC-51Cr half-life and albumin turnover in growing beagle dogs during chronic radial acceleration.

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The effects of chronic centrifugation on growing Beagle dogs exposed to -2 or -2.6 Gx on albumin and RBC turnover rates, albumin concentration and space, and total blood volume were determined and compared with caged and run control animals. Albumin-125I and autologous RBC-51Cr preparations were

[Systemic capillary leak syndrome presenting remarkable erythrocytosis].

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Systemic capillary leak syndrome (SCLS) is a disorder characterized by hypotension, edema, and an increased hematocrit (Ht) due to sudden leakage of plasma into the extravascular space through some unknown mechanism, in which monoclonal gammopathy is observed. A 30-year-old man visited our emergency

Acute polycythemia increases the disappearance rate of clottable fibrinogen in the newborn dog.

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To explore the pathophysiology of the necrotizing enterocolitis caused by polycythemia in the newborn dog, the effect of acute polycythemia on fibrinogen disappearance rate was studied in 38 puppies (3-14 days). All pups received an exchange transfusion removing 65 ml/kg of blood and transfusing 85

Hypoalbuminemia in donors with twin anemia-polycythemia sequence: a matched case-control study.

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OBJECTIVE To determine the differences in albumin levels between donors and recipients with twin anemia-polycythemia sequence (TAPS). METHODS We included all consecutive monochorionic twins with TAPS with double survivors. Each twin pair was matched for gestational age at birth with 2 control

Erythrocytosis in spontaneously hypertensive rats.

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During the study of an inbred strain of Wistar rats which spontaneously develop hypertension when they reach a weight of approximately 150 g, it was found that these animals also develop an erythrocytosis. A significant increase in red cell count was observed in spontaneously hypertensive (SH) rats

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