polygala nicaeensis/anti aging

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Neuroprotective effects of tenuigenin in a SH-SY5Y cell model with 6-OHDA-induced injury.

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Tenuigenin, an active component of Polygala tenuifolia root extracts, has been shown to provide antioxidative and anti-aging effects in Alzheimer's disease, as well as to promote proliferation and differentiation of neural progenitor cells. However, the effects of tenuigenin on Parkinson's disease

Tenuigenin promotes proliferation and differentiation of hippocampal neural stem cells.

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The present study was to investigate the influence of tenuigenin, an active ingredient of Polygala tenuifolia Willd, on the proliferation and differentiation of hippocampal neural stem cells in vitro. Tenuigenin was added to a neurosphere culture and neurosphere growth was measured using MTT assay.

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