port-wine stain/nicotine

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Nicotine-based surface active ionic liquids: Synthesis, self-assembly and cytotoxicity studies.

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New ester-functionalized surface active ionic liquids (SAILs) based on nicotine, [CnENic][Br] (n=8, 10 and 12), with bromide counterions have been synthesized, characterized and investigated for their self-assembly behavior in aqueous medium. Conductivity measurements in aqueous solutions of the

Genotoxicity of yellow shammah (smokeless tobacco) in murine bone marrow cells in vivo.

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Shammah is a traditional form of smokeless tobacco (ST) that is manufactured and used locally by people of Middle East with highest usage in Saudi Arabia, Yemen and Sudan. In Saudi Arabia, shammah comes in three variants: white, brown and yellow. In the present study, we investigated the

Synergistic effects of 2A-mediated polyproteins on the production of lignocellulose degradation enzymes in tobacco plants.

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Cost-effective bioethanol production requires a supply of various low-cost enzymes that can hydrolyse lignocellulosic materials consisting of multiple polymers. Because plant-based enzyme expression systems offer low-cost and large-scale production, this study simultaneously expressed β-glucosidase

In vivo assessment of genotoxic potential of brown shammah (smokeless tobacco) in bone marrow cells of mice.

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This study was aimed to assess the genotoxicity of brown shammah (BS), a local form of smokeless tobacco, popular in Middle East countries including Yemen, Saudi Arabia and Sudan. The genotoxicity was explored using in vivo chromosomal aberration (CA), micronucleus (MN) and sperm abnormality

Comparison of Thermobifida fusca Cellulases Expressed in Escherichia coli and Nicotiana tabacum Indicates Advantages of the Plant System for the Expression of Bacterial Cellulases.

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The economic conversion of lignocellulosic biomass to biofuels requires in addition to pretreatment techniques access to large quantities of inexpensive cellulases to be competitive with established first generation processes. A solution to this problem could be achieved by plant based expression of

Inhibition of tobacco etch virus protease activity by detergents.

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Affinity tags such as polyhistidine greatly facilitate recombinant protein production. The solubility of integral membrane proteins is maintained by the formation of protein-detergent complexes (PDCs), with detergent present at concentration above its critical micelle concentration (CMC). Removal of

Determining population stratification and subgroup effects in association studies of rare genetic variants for nicotine dependence.

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Rare variants (minor allele frequency < 1% or 5 %) can help researchers to deal with the confounding issue of 'missing heritability' and have a proven role in dissecting the etiology for human diseases and complex traits.We extended the combined

Comparative effects of cilostazol and aspirin on the impairment of endothelium-dependent cerebral vasodilation caused by acute cigarette smoking in rats.

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We previously reported that acute cigarette smoking can cause a dysfunction of endothelium-dependent vasodilation in cerebral vessels, and that a reduction of oxidative stress by agents such as valsartan, fasudil, or apocynin prevented this impairment. Here, our aim was to investigate the

Combined fibroblast growth factor receptor 4 cell membrane chromatography online with high performance liquid chromatography/mass spectrometry to screen active compounds in Brassica albla.

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We investigated an analytical method for the recognition separation, and identification of active components from the traditional Chinese medicinal plant Brassica albla L. using fibroblast growth factor receptor 4 cell membrane chromatography (FGFR4/CMC) with high performance liquid

Antioxidative effect of folate-modified chitosan nanoparticles.

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OBJECTIVE To evaluate the potency of carboxymethyl chitosan-2, 2' ethylenedioxy bis-ethylamine-folate (CMC-EDBE-FA) on tissue injury, antioxidant status and glutathione system in tissue mitochondria and serum against nicotine-induced oxidative stress in mice. METHODS CMC-EDBE-FA was prepared on

Parental Educational Attainment and Chronic Medical Conditions among American Youth; Minorities' Diminished Returns.

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Parental educational attainment is protective against chronic medical conditions (CMCs). According to the minorities' diminished returns (MDRs) theory, however, the health effects of socioeconomic status (SES) indicators are smaller for socially marginalized groups such as racial and

Suppression of Strong Background Interference on E-Nose Sensors in an Open Country Environment.

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The feature extraction technique for an electronic nose (e-nose) applied in tobacco smell detection in an open country/outdoor environment with periodic background strong interference is studied in this paper. Principal component analysis (PCA), Independent component analysis (ICA), re-filtering and

Short- and long- term effects of cigarette smoke exposure on glutathione homeostasis in human bronchial epithelial cells.

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BACKGROUND Cigarette smoke extract (CSE), a model for studying the effects of tobacco smoke in vivo and in vitro, induces cell oxidative stress and affects the antioxidative glutathione system. We evaluated the impact of CSE on airway epithelial cells and the possible cytoprotective effect of the

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