prehypertension/diarrhea

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Chronic renal disease is more prevalent in patients with hemolytic uremic syndrome who had a positive history of diarrhea.

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Many uncontrolled studies and a subsequent meta-analysis suggest that hemolytic uremic syndrome (HUS) with a positive history for diarrhea is associated with a significant increase in chronic renal disease. Two recent controlled studies that followed children with this type of HUS after Escherichia

Hypomagnesemia and prehypertension in otherwise healthy individuals.

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BACKGROUND Given the potential implications in the policies focused on the prevention of hypertension, we evaluate the relationship between low serum magnesium levels and prehypertension in otherwise healthy subjects. METHODS A cross-sectional study that enrolled 175 healthy men and non-pregnant

Effect of oral magnesium supplementation on the transcription of TRPM6, TRPM7, and SLC41A1 in individuals newly diagnosed of pre-hypertension. A randomized, double-blind, placebo-controlled trial.

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A stringent regulation of influx and efflux of magnesium by cation transporters seems to play an important role in the regulation of blood pressure (BP). With this regard, we evaluate the effect of oral magnesium supplementation on the transcription of TRPM6, TRPM7, and SLC41A1, in individuals with

Prospective, randomized, double-blinded, placebo-controlled study on safety and tolerability of the krill powder product in overweight subjects with moderately elevated blood pressure.

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Krill powder is rich in bioactive ingredients such as eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), phospholipids, protein and astaxanthin. Containing dominantly EPA, it is considered to be effective in lowering lipids, foremost serum triglycerides and LDL cholesterol.

Early childhood diarrhea and cardiometabolic risk factors in adulthood: the Institute of Nutrition of Central America and Panama Nutritional Supplementation Longitudinal Study.

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BACKGROUND Nutritional deficits in early life have been associated with a higher prevalence of the metabolic syndrome (MetS) in adulthood. Early childhood diarrhea contributes to undernutrition and may potentially increase the risk for adult noncommunicable diseases. Our objective was to examine

Prevalence of Prehypertension in Mexico and Its Association With Hypomagnesemia.

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BACKGROUND Prehypertension (preHTN) increases the risk of developing hypertension. The objectives of this study were to estimate the prevalence of preHTN in the Mexican adult population and evaluate the association between hypomagnesemia and preHTN. METHODS This study was a 2-phase, population-based

Low Serum Magnesium Levels and Its Association with High Blood Pressure in Children.

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OBJECTIVE To evaluate the association of hypomagnesemia with prehypertension (preHTN) and hypertension in children. METHODS A total of 3954 apparently healthy Mexican children were enrolled in a cross-sectional study. Exclusion criteria were type 2 diabetes; hepatic, renal, or endocrine disease;

Effects of fostamatinib, an oral spleen tyrosine kinase inhibitor, in rheumatoid arthritis patients with an inadequate response to methotrexate: results from a phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study.

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OBJECTIVE This phase III, 52-week study compared fostamatinib with placebo (for 24 weeks) in patients with active rheumatoid arthritis (RA) and an inadequate response to methotrexate (MTX) therapy. METHODS Patients taking MTX were randomized (1:1:1) to receive fostamatinib 100 mg twice daily for 52

[The role of orlistat in the treatment of obesity].

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The overweight and obesity represent severe problems for the health management system of developed countries. In the evolution of obesity, beside genetic background, the environmental factors also play important roles. In the daily routine, the majority of obese patients need drug treatment, over

Yersinia enterocolitica bacteremia associated with red blood cell transfusion.

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A chronically ill, 80-year-old man received over three fourths of a unit of CPDA-1 red blood cells contaminated with Yersinia enterocolitica serotype 0:3. He experienced rigors, high fever, elevated blood pressure, and increased pulse rate. He was treated with antibiotics and discharged in stable

Leukocytoclastic vasculitis with late-onset Henoch-Schönlein purpura after trifluridine/tipiracil treatment.

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Trifluridine/tipiracil has been approved for the treatment of refractory metastatic colorectal cancer. Adverse effects of this drug combination include leukopenia, neutropenia, fatigue, diarrhea, and vomiting. We present a case of trifluridine/tipiracil-induced leukocytoclastic vasculitis (LCV) with

Quetiapine-induced thrombotic microangiopathy in a patient on maintenance dialysis

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Quetiapine has been reported to cause immune-mediated thrombotic microangiopathy (TMA), although few cases have been reported thus far. A 71-year-old man with autosomal dominant polycystic kidney disease on maintenance dialysis was hospitalized with a hemorrhagic basal ganglia stroke, and was

Constituents and biological activity of the essential oil and the aqueous extract of Micromeria fruticosa (L.) Druce subsp. serpyllifolia.

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Micromeria fruticosa L Druce subsp. serpyllifolia is a medicinal herb that is widely used as folk medicine in the treatment of abdominal pains, diarrhea, eye infections, heart disorders, elevated blood pressure, colds and wounds. This study aims to investigation the constituents and biological

Developing world perspective: the importance of growth for short-term health.

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Recently, concern has been raised about the potential adverse long-term consequences of rapid child growth. Rapid early childhood weight gain is associated with increased likelihood of being overweight or obese later in childhood and of having risk factors for the development of chronic disease such

A phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study of 2 dosing regimens of fostamatinib in patients with rheumatoid arthritis with an inadequate response to a tumor necrosis factor-α antagonist.

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OBJECTIVE Our 24-week study (NCT01197755; OSKIRA-3) compared the efficacy and safety of fostamatinib versus placebo in patients taking background methotrexate treatment with active rheumatoid arthritis (RA) and an inadequate response to a single tumor necrosis factor-α antagonist. METHODS Adult

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