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primary immunodeficiency diseases/obesity
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Compositions and methods for treating obesity, obesity related disorders and for inhibiting the infectivity of human immunodeficiency virus
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FIELD OF THE INVENTION
The present invention relates generally to methods and compositions for modulating the body weight of mammals including animals and humans, and more particularly to materials identified herein as modulators of weight, and the use of these materials for treating obesity and
Compositions and methods for treating obesity, obesity related disorders and for inhibiting the infectivity of human immunodeficiency virus
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FIELD OF THE INVENTION
Background of the Invention
Obesity, which is defined in general terms as an excess of body fat relative to lean body mass, is now a world wide epidemic, and is one of the most serious contributors to increased morbidity and mortality. Obesity is prevalent in the United
Methods of treating obesity by administering a TAT peptide
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BACKGROUND
1. Field of the Invention
The present invention relates to a composition for preventing, alleviating or treating obesity comprising partial fragments of Tat (Trans activator of transcription).
2. Background of Technique
Wasting is a major cause of morbidity and mortality associated with
Pyridazinone derivatives, methods for their production and their use as pharmaceuticals
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FIELD OF THE INVENTION
The present invention relates generally to the treatment and therapy of certain metabolic diseases such as neurodegenerative diseases such as Alzheimer's disease, Parkinsons' Disease, multiple sclerosis and diabetes. More specifically, the present invention relates to novel
Use of aminoindazole derivatives for the inhibition of tau phosphorylation
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BACKGROUND OF THE INVENTION
The present invention relates to the use of derivatives of formula (I):
##STR00002## or their pharmaceutically acceptable salts as kinase inhibitor.
The subject matter of the invention is the use of the aminoindazole derivatives of formula (I) and their pharmaceutically
Aminoindazole derivatives as medicaments and pharmaceutical compositions including them
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BACKGROUND OF THE INVENTION
The present invention relates to the use of derivatives of formula (I):
##STR00002## or their pharmaceutically acceptable salts as kinase inhibitor.
The subject matter of the invention is the use of the aminoindazole derivatives of formula (I) and their pharmaceutically
Aminoindazole derivatives as medicaments and pharmaceutical compositions including them
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BACKGROUND OF THE INVENTION
The present invention relates to the use of derivatives of formula (I):
##STR00002## or their pharmaceutically acceptable salts as kinase inhibitor.
The subject matter of the invention is the use of the aminoindazole derivatives of formula (I) and their pharmaceutically
Piperidine derivative compounds and drugs containing the compounds as the active ingredient
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TECHNICAL FIELD
The present invention relates to a piperidine derivative.
More specifically, the present invention relates to (1) a piperidine derivative of formula (I)
##STR00002## (2) a method for the preparation thereof, (3) a composition comprising it as an active ingredient, (4) a compound of
Use of L-acetylcarnitine, L-isovalerylcarnitine, L-propionylcarnitine for increasing the levels of IGF-1
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The present invention relates to a novel therapeutic use of L-acetylcarnitine, L-isovalerylcarnitine, L-propionylcarnitine or pharmacologically acceptable salts thereof for increasing the levels of IGF-1(insulin-like growth factor 1) for the therapeutic treatment or prophylaxis or cytological
Use of L-acetylcarnitine, L-isovalerylcarnitine, L-propionylcarnitine for increasing the levels of IGF-1
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This is a 371 of PCT/IT97/00113 filed May 15, 1997.
The present invention relates to a novel therapeutic use of L-acetylcarnitine, L-isovalerylcarnitine, L-propionylcarnitine or pharmacologically acceptable salts thereof for increasing the levels of IGF-1 (insulin-like growth factor 1) for the
Bicyclic inhibitors of glycogen synthase kinase 3
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FIELD OF THE INVENTION
This invention relates to new bicyclic compounds that inhibit the activity of glycogen synthase kinase 3 (GSK3), to pharmaceutical compositions containing the compounds and to the use of the compounds and compositions, alone or in combination with other pharmaceutically active
Carbocycle based inhibitors of glycogen synthase kinase 3
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FIELD OF THE INVENTION
This invention relates to carbocyclic compounds that inhibit the activity of glycogen synthase kinase 3 (GSK3), to pharmaceutical compositions containing the compounds and to the use of the compounds and compositions, alone or in combination with other pharmaceutically active
Thiazole derivatives
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FIELD OF THE INVENTION
The subject invention relates to thiazole derivatives, pharmaceutical compositions comprising such derivatives and methods of using such derivatives to treat abnormal cell growth and certain diseases and conditions of the central nervous system. The compounds of the present
Imidazole derivatives
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FIELD OF THE INVENTION
The subject invention relates to imidazole derivatives, pharmaceutical compositions comprising such derivatives and methods of using such derivatives to treat abnormal cell growth and certain diseases and conditions of the central nervous system. The compounds of the present
Imidazole derivatives
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FIELD OF THE INVENTION
The subject invention relates to imidazole derivatives, pharmaceutical compositions comprising such derivatives and methods of using such derivatives to treat abnormal cell growth and certain diseases and conditions of the central nervous system. The compounds of the present
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