primary ovarian insufficiency/hypoxia

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Ovarian sickling as a proposed mechanism for premature ovarian failure necessitating ovum donation.

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Iron overload in female patients with sickle cell disease (SCD) has been reported to result in gonadal dysfunction. To date there has been no report in the literature of ovarian sickling being a reason for gonadodysgenesis (premature ovarian failure [POF]) in women. This case report describes POF in

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