Emergencies in HIV-infected patients are a common complication which may occur at any stage of the disease. Opportunistic infections may lead to irreversible damages of organs such as the brain, the eye or the lung. With the widely use of antiretroviral therapy side effects of reverse transcriptease
Gabexate mesilate (GM), a potent synthetic proteinase inhibitor has been evaluated as an alternative anticoagulant to heparin for haemodialysis. GM haemodialysis was achieved at a dose of 1,600mg/hr. GM was found to be dialysable and so rapidly degraded that dialysis with GM anticoagulation was
The basic proteinase inhibitor from bovine organs, aprotinin, was first identified in 1930 and its effect on enzyme and other biological systems has since been extensively studied. Aprotinin can only be administered intravenously and has a half-life of about 2 hours. Its administration at the start
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