psilostachyin/ambrosia artemisiifolia

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Modulation of the G2 cell cycle checkpoint by sesquiterpene lactones psilostachyins A and C isolated from the common ragweed Ambrosia artemisiifolia.

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A phenotypic cell-based assay for inhibitors of the G (2) DNA damage checkpoint was used to screen plant extracts from the US National Cancer Institute Natural Products Repository. It revealed activity in a methanol extract from the common ragweed Ambrosia artemisiifolia. Assay-guided fractionation

Isolation and identification of psilostachyin B from Ambrosia artemisiifolia L.

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Ambrosia artemisiifolia as a potential resource for management of golden apple snails, Pomacea canaliculata (Lamarck).

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BACKGROUND Ambrosia artemisiifolia, an invasive weed in Europe and Asia, is highly toxic to the golden apple snail (GAS; Pomacea canaliculata) in laboratory tests. However, little is known about the chemical components of A. artemisiifolia associated with the molluscicidal activity or about its

[Chemical constituents of ragweed (Ambrosia artemisiifolia L.)].

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Three sesquiterpene lactones isolated from the aerial parts of Ambrosia artemisiifolia were identified as psilostachyin, psilostachyin B and psilostachyin C. All of them have some molluscicidal activity against Oncomelania hupensis.

Natural terpenoids from Ambrosia species are active in vitro and in vivo against human pathogenic trypanosomatids.

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Among the natural compounds, terpenoids play an important role in the drug discovery process for tropical diseases. The aim of the present work was to isolate antiprotozoal compounds from Ambrosia elatior and A. scabra. The sesquiterpene lactone (STL) cumanin was isolated from A. elatior whereas two

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