pteridium esculentum/edema

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The hemolytic activity of bracken extracts in guinea pigs.

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This study was conducted to elucidate the hemolytic activity of a new toxic substance in bracken fern. A crude extract (CE) was prepared from the methanol extracts of bracken by the column chromatography. When the CE was injected subcutaneously in guinea pigs, the hemoglobinuria and hemolysis were

Non-urotoxic induction of hemorrhagic cystitis by braxin C, a bracken toxin, in guinea pigs.

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Single subcutaneous injections of 5 and 10 mg/kg of braxin C (BC), ptaquiloside, a toxin isolated from bracken fern, have been shown to induce hemorrhagic cystitis in guinea pigs. In order to determine whether the hemorrhagic cystitis induced by BC is due to the urotoxic effects or not, BC was

Acute toxicity of braxin C, a bracken toxin, in guinea pigs.

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Braxin C (BC), ptaquiloside, is a toxin isolated from bracken fern. In order to determine the characteristics of the acute BC toxicity, BC was administered as a single subcutaneous (s. c.) injection to guinea pigs, rats, and mice. BC (5 and 10 mg/kg) induced hemorrhagic cystitis and hematuria in

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