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pteridium esculentum/neoplasms

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Bracken-fern extracts induce cell cycle arrest and apoptosis in certain cancer cell lines.

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Bracken fern [Pteridium aquilinem (L.) kuhn (Dennstaedtiaceae)] is one of the most common species on the planet. It has been consumed by humans and animals for centuries. Use by some human groups is because they believe bracken fern is good for health as plant medicine. However, it is also one of

Alpha-ecdysone, a new bracken fern factor responsible for neoplasm induction in the Egyptian toad (Bufo regularis).

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Neoplastic lesions were induced in 10 out of 58 experimental toads (Bufo regularis) force-fed with alpha-ecdysone, which naturally occurs in the leaves of bracken fern (Pteris aquilina). The results of this study prove that alpha-ecdysone may be one of the factors responsible for the carcinogenicity

Induction of tumors of the urinary bladder in female mice following surgical implantation of glass beads and feeding of bracken fern.

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The carcinogenic effect of bracken fern (Pteris aquilina) to the urinary bladder of mice was studied. Powdered bracken fern mixed with a basic commercial diet (1:4 by weight) was fed to a group of 40 ICR strain mice for 20 weeks after the implantation of a glass bead into the bladder. A total

Induction of tumors in rats by bracken fern (Pteridium aquilinum) from Ouro Preto (Minas Gerais, Brazil).

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1. The possible carcinogenicity of bracken fern (Pteridium aquilinum, common name: "Broto de Samambaia") which is used as food by the population of Ouro Preto (Minas Gerais, Brazil) and neighboring areas, was studied in rats. 2. Fifteen (6 female and 9 male) 45-day old Wistar rats were fed a diet

Histogenesis of urinary bladder cancer induced in rats by bracken fern.

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Histologic examination of the urinary bladders of albino rats fed bracken fern (Pteris aqulinum) showed epithelial hyperplasia in all test animals after 3 weeks of feeding and nuclear abnormalities at 4 to 6 weeks. Epithelial tumors were present in animals surviving more than 12 weeks, and invasion

Bracken fern, phenacetin, and cancer of the urinary tract.

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Bracken fern, a forage contaminant, is causally related to urinary bladder cancer in animals. In this review of experimental studies on carcinogenesis of bracken fern, little evidence of an association between cancer and bracken fern in humans was observed. Clinicoepidemiological studies have shown

Bracken fern-induced malignant tumors in rats: absence of mutations in p53, H-ras and K-ras and no microsatellite instability.

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Bracken fern (genus Pteridium) has been shown to induce tumors in domestic and experimental animals. Epidemiological studies have also shown an association between human exposure to bracken toxins and increased risk for the development of upper gastrointestinal tract tumors. Our aim in this study

Bracken fern-induced bladder tumors in guinea pigs. A model for human neoplasia.

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We have induced tumors by feeding guinea pigs with a diet containing 25 or 30% dried bracken fern for 100 or 150 days. A high incidence of bladder tumors was obtained. All but one animal had preneoplastic or neoplastic lesions after 4 months; after one year, 24 or 25 exposed animals had carcinoma.

Association of bovine papillomavirus type 2 and bracken fern with bladder cancer in cattle.

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The bladder cancer syndrome that often accompanies chronic enzootic hematuria in cattle grazing on pastures infested by bracken fern has been experimentally reproduced in animals fed a diet of bracken. The experimentally induced tumors were histologically and pathologically indistinguishable from

Possible association between gastric cancer and bracken fern in Venezuela: an epidemiologic study.

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To explore a possible connection between specific environmental factors that might explain the high rates of stomach cancer in people living in the highlands of western Venezuela, an epidemiologic study was conducted in 2 regions of contrasting topography. The regions embrace 3 Andean states,

Bracken fern (Pteridium aquilinum) ingestion and oesophageal and stomach cancer.

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Bracken fern consumption and human bladder cancer.

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Histopathogenesis of intestinal tumors induced by oral administration of bracken fern, Pteridium aquilinum in rats.

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Induction of intestinal and urinary bladder cancer in rats by feeding bracken fern (Pteris aquilina).

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Bracken fern and papilloma virus in bovine alimentary cancer.

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