purpura fulminans/atrophy

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[High-dose heparin in a patient with purpura fulminans following varicella].

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We report on a 3 1/2 year old girl with purpura fulminans after varicella who made a complete recovery on treatment with an appropriate high-dose heparin regimen and other supporting measures. Several attempts to reduce the heparin dosage from the initial high level (85 IU/kg/hour) to the usual

Purpura Fulminans in Toxic Epidermal Necrolysis: Case Report and Review.

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Purpura fulminans (PF) and toxic epidermal necrolysis (TEN) are rare and life-threatening diseases. TEN is a notorious epidermolytic condition, most cases of which are drug induced. TEN is a more severe variant of epidermal necrolysis than Stevens-Johnson syndrome, as it affects a greater percentage

Bilateral torsion of testes with purpura fulminans.

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BACKGROUND Purpura fulminans and bilateral perinatal testicular torsion are rare and may co-exist. METHODS A 3-day-old neonate with bilateral swelling of scrotum; torsion and gangrenous changes were observed on exploration. METHODS Left orchidectomy with preservation of right testis was

Musculoskeletal sequelae of Varicella-zoster infection: two case reports.

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Varicella-zoster is a common paediatric viral infection that usually runs a benign self-limiting course but has a risk of complications. The most common sequelae are bacterial skin infections, which are usually mild. However, bacteraemia/septic shock, toxic shock syndrome, pneumonia, ataxia,

Severe protein C deficiency in a newborn.

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An infant presented at birth with a cutaneous lesion that developed the characteristics of purpura fulminans. He sustained a cerebral infarction during the first 4 days of life, which was initially misinterpreted to be cerebral hemorrhage resulting from thrombocytopenia and hypofibrinogenemia. After

Identification of PROS1 as a Novel Candidate Gene for Juvenile Retinitis Pigmentosa

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Homozygous mutations of PROS1, encoding vitamin K-dependent protein S (PS), have been reported so far to be associated with purpura fulminans, a characteristic fatal venous thromboembolic disorder. The current work for the first time reports the clinical phenotype in patients with juvenile retinitis

Cutaneous pseudovasculitis.

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Cutaneous pseudovasculitis represents a heterogeneous collection of disorders that are capable of simulating cutaneous vasculitis and can be broadly classified into diseases that produce hemorrhage (petechiae, purpura, and ecchymoses) or vessel occlusion with resultant livedo, cyanosis, ulcers,

Pediatric critical care management of septic shock prior to acute kidney injury and renal replacement therapy.

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A high index of suspicion for bacterial sepsis and recognition of the potential for rapid deterioration is essential for impacting patient outcome. Meningococcemia produces a stereotypical clinical and biochemical constellation of profound septic shock and purpura fulminans with marked inflammatory

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