purpura/fever

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Arthritis in Assiut University Children Hospital

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Arthritis is defined as inflammation of the joint, Patients have symptoms of joint pain, stiffness, swelling, redness, warmth and decreased range of motion of the affected joints. Arthritis may be caused by transient synovitis, juvenile idiopathic arthritis ( JIA), reactive arthritis, viral

Efficacy of Colchicine to Prevent Skin Relapses in Adult's IgA Vasculitis

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Immunoglobulin A vasculitis (IgA-V), formerly called Henoch-Schönlein purpura, is an immune vasculitis. Relapses are frequent (30%) and most of the time cutaneous (90%). Cutaneous involvement in adults is more severe (haemorrhagic blister or necrotic skin lesions) and more extensive than in

Chronic Myloid Leukemic Patients Treated With Tyrosine Kinase Inhibitor

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Chronic myelogenous leukemia (CML) is a myeloproliferative disorder in which leukemic cells display the Philadelphia chromosome generated from a reciprocal t(9:22) (q34:q11) translocation.1 The chromosome 9 and chromosome 22 transposal of t (9:22) and (q34:q11) causes the cancer gene C-ABL at 9q34

Evaluation of Different Methods for Diagnosis of ME

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meningitis is a notifiable disease in many countries, the exact incidence rate is unknown. In 2013 meningitis resulted in 303,000 deaths - down from 464,000 deaths in 1990. In 2010 it was estimated that meningitis resulted in 420,000 deaths, excluding cryptococcal meningitis. Bacterial meningitis

Petechiae In Children (PIC) Study: Defining A Clinical Decision Rule for The Management Of Fever and Non-Blanching Rashes In Children Including The Role Of Point Of Care Testing For Procalcitonin & Neisseria Meningitidis DNA.

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A fever an a non-blanching rash is a relatively common presentation the the emergency department. A minority of children with a fever and a non-blanching rash with have a life-threatening infection. Currently it is very difficult to determine those children that require urgent treatment from those

Diagnosis of Ascites in Infants and Children

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Definition : Ascites is the pathologic fluid accumulation within the peritoneal cavity . causes of ascites in infants and children : - Hepatobiliary disorders (cirrhosis, congenital hepatic fibrosis, acute hepatitis B,C ,Budd -chiari syndrome, Bile duct perforation) - Serositis (crohn's disease,

NATIENS: Optimal Management and Mechanisms of SJS/TEN

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Background and Scientific Rationale Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are severe, life-threatening immunologically mediated adverse drug reactions representing the same disease across a spectrum of severity that affect 60,000 patients per year globally at an

Measurement of Antibodies in Adults With a History of Kawasaki Disease

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Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation

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1.0 Background While atrial fibrillation (AF) is the most common sustained cardiac arrhythmia requiring therapy, it is also associated with increased risk of stroke, heart failure, myocardial infarction, dementia, and death. The number of Americans affected with AF is expected to surge to nearly 16

Safety and Efficacy Study of Intravenous Immunoglobulin to Treat Japanese Encephalitis

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Japanese encephalitis (JE) is the most important epidemic encephalitis worldwide, causing approximately 35-50,000 cases and 10-15,000 deaths annually. Half of the survivors have severe neuropsychiatric sequelae, posing a large socio-economic burden on communities that can ill afford it. JE virus

Thermographic Characteristics of Sore Throat by Thermographic Camera

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Patients aged between 5 years and 18 years, who attend the primary health clinic for medical treatment with a complaint of only sore throat and fever will be offered to participate in the study and have a thermal camera photo of the tonsils. The study group will consist of 100 patients. Fifty

Pakistan Epidemiological Survey in Acute Pharyngitis

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Pharyngitis is a common reason for patients' visit to doctors. Group A beta- hemolytic streptococci (GABHS) account for 15-30 percent of cases of acute pharyngitis in children and 5 to 20 percent in adults1. Because the signs and symptoms of GABHS pharyngitis overlap extensively with other

Prevalence and Early Markers of Atherosclerosis in Adults With a History of Kawasaki Disease

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Study of a Novel Tetravalent Dengue Vaccine in Healthy Children Aged 2 to 14 Years in Asia

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Participants were randomized to either receive 3 injections of CYD dengue vaccine or a placebo at 0, 6, and 12 months. A subset of participants from each country were also evaluated for reactogenicity and immunogenicity. Participants who consented to participate in the SEP were actively followed for

Efficacy and Safety of Dengue Vaccine in Healthy Children

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Participants (both cohort 1 and 2) received 3 injections of CYD dengue vaccine. Participants (Cohort 1) received rabies vaccine at Month 0 and placebo at 6 and 12 months. Participants (cohort 2) received placebo at 0, 6, and 12 months. Dengue cases were collected for assessment of efficacy during

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