Phlai 2 capsules (compound D 8 mg) od evening after meal x 4 weeks

Phlai 1 capsules (compound D 4 mg) and placebo 1 capsule od evening after meal x 4 weeks

Placebo 2 capsules od evening after meal x 4 weeks

Allergic Rhinitis

Each capsule contains 4 mg compound D. Using orally in the evening everyday in 4 weeks

Phlai

Like Phlai capsule extract : :PVP K30, Calcium carbonate, Dibasic calcium phosphate, Sodium starch glycolate, Colloidal silicon dioxide, Ethanol 96%, Purified water, Magnesium stearate. Not having compound D. Using orally in the evening everyday in 4 weeks

Placebo oral capsule

Minh Phuoc Hoang, MD

"Efficacy and Safety of Phlai Capsule Compared to Placebo as the Treatment in Allergic Rhinitis Patients"

T5SS: (nasal obstruction, rhinorrhea, sneezing, itchy nose, itchy eyes). For each symptom:
0: no symptoms
mild
moderate
severe. Participants assess T5SS everyday. Self assessment twice a day Bedtime : reflective symptoms score Morning :instantaneous symptoms score. The mean score of two assessment is the T5SS. Investigator will calculate the mean T5SS in the follow up

This questionnaire is designed to find out how your health and well-being have been affected by rhinoconjunctivitis.

Use to measure nasal airflow during maximal inspiration

Outcome assessor in each site will check the three symptoms: nasal swelling, pale and nasal discharge by anterior rhinoscopy

Will plan to share information when finishing study

Principal Investigator

Chulalongkorn University

Government Pharmaceutical Organization

Participant in each arm will take medication provided by care providers who also do not know what kind of this medication

Participant, care provider and investigator, outcomes assessor in each site do not know what kind of medication in each package.

25 participants with radiopaque stones (Calcium Oxalate) treated with Luban (AKBA-Incense 2 capsules daily, 30% 3-acetyl-11-keto-ß-boswellic acid, from ZeinPharma)

25 participants with radiopaque stones (Calcium Oxalate) treated with Uralyt-U (Potassium Sodium Hydrogen Citrate, 10g orally in 3 divided doses with pH target 6.2-6.8)

25 participants with radiolucent stones (Uric acid) treated with Luban (AKBA-Incense 2 capsules daily, 30% 3-acetyl-11-keto-ß-boswellic acid, from ZeinPharma)

25 participants with radiolucent stones (Uric acid) treated with Uralyt-U (Potassium Sodium Hydrogen Citrate, 10g orally in 3 divided doses with pH target 7.0-7.2

Renal Stones

AKBA-Incense 2 capsules daily, 30% 3-acetyl-11-keto-ß-boswellic acid, from ZeinPharma

AKBA-Incense (3-acetyl-11-keto-ß-boswellic acid)

Uralyt-U (Potassium Sodium Hydrogen Citrate, 10g orally in 3 divided doses with pH target 6.2-6.8 for Calcium Oxalate stones and 7.0-7.2 for Uric Acid stones)

Potassium Sodium Hydrogen Citrate

Mohamed Salim Ahmed Al-Marhoon

Treatment of Renal Stones With Frankincense (Luban)

Treatment of Renal Stones With Frankincense (Boswellic Acid): A Clinical Randomized Trial

The participants intolerance of the treatment or development of side effects that are not known complications of the presence of stones or new adverse reactions

Senior Consultant Urological Surgeon and Head of Urology

Sultan Qaboos University

The essential plai cream has anti-inflammatory and antimicrobial effects (Wasuwat1989, Giwanon 2000, Pithayanukul 2007, and Tripathi 2008). Active chemicals of plai cream are composed of sabinene, alpha and gamma tepinenes, terpinen 4-ol and (E)-1-(3,4-dimethoxyphenyl butadiene (DMPBD). The DMPBD has a property of anti-inflammatory activity(Ozaki 1991, Jeenapongsa 2003). Plavina® 40 mg in 100 gm (contains DMPBD of …%). This product was supplied in lacquered aluminum collapsible tube containing 100 gram cream packing.

Knee Osteoarthritis

Plavina cream

Department of Orthopedics, Faculty of Medicine, Khon Kaen University, Thailand

Faculty of Medicine KhonKaen University

Efficacy Study on Symptomatic Control of Patient With Knee Osteoarthritis Between 14% of Plai (Plaivana®) to Placebo Gels

The WOMAC score is a tri-dimensional, disease-specific, self-administered health status measure, probing clinically important, subject-relevant symptoms in the area of pain. The subject will answer WOMAC question on pain subscale, using the Linkert scale 0-100 at screening 1st visit to determine eligibility for inclusion in the study. The subject will complete the entire WOMAC questionnaire during visit 2-13 (week 1-12)

remusatia/inflammation

"Efficacy and Safety of Phlai Capsule Compared to Placebo as the Treatment in Allergic Rhinitis Patients"

Treatment of Renal Stones With Frankincense (Luban)

Efficacy Study on Symptomatic Control of Patient With Knee Osteoarthritis Between 14% of Plai (Plaivana®) to Placebo Gels

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