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Novel flavagline-like compounds with potent Fli-1 inhibitory activity suppress diverse types of leukemia.
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E26 transformation-specific (ETS) gene family contains a common DNA-binding domain, the ETS domain, responsible for sequence-specific DNA recognition on target promoters. The Fli-1 oncogene, a member of ETS gene family, plays a critical role in hematopoiesis and is overexpressed in diverse
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