salicylate/vomiting

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Evaluation of the efficacy of lavage and induced emesis in treatment of salicylate poisoning.

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Comparison of ipecac-induced emesis with gastric lavage in the treatment of acute salicylate ingestion.

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THE MECHANISM OF THE EMETIC ACTION OF SODIUM SALICYLATE.

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In the dog, the emetic ED50 for sodium salicylate was 256+/-113 mg/kg for the intravenous route with a mean latency of 10.4+/-3.96 min, and for the oral route 228+/-68 mg/kg with a mean latency of 18.2+/-2.63 min. Values are means with standard errors. Ablation of the emetic chemoreceptor

Salicylate-induced seizures in a dog.

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A 10-year-old, mixed-breed, castrated male dog was examined because of acute onset of vomiting followed by severe generalized seizures. The dog had been on a treatment regimen that included a salicylate-containing drug, and the owners unknowingly supplemented aspirin. Supportive treatment utilizing

Candy flavoring as a source of salicylate poisoning.

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Methyl salicylate (oil of wintergreen) in the form of candy flavoring was ingested by a 21-month-old male infant who subsequently developed vomiting, lethargy, and hyperpnea. A "swallow" of the solution resulted in a serum salicylate concentration of 81 mg/dL six hours after ingestion. The infant

Salicylate toxicity from ingestion of traditional massage oil.

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A 16-month-old child developed a brief generalised tonic-clonic fitting episode and vomiting at home, after accidental ingestion of traditional massage oil. As the patient presented with clinical features of salicylate toxicity, appropriate management was instituted. He was admitted to the intensive

Serum salicylate concentrations in Reye's disease. A study of 130 biopsy-proven cases.

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Serum salicylate concentration was measured at admission in 130 children with liver-biopsy-confirmed Reye's disease. Mean serum salicylate was 12.3 mg/dl and mean salicylate concentrations by neurological grade (Lovejoy) were: stage I, 12, stage II, 13, stage III, 11, stage IV, 13, and stage V, 13

Acute methyl salicylate toxicity complicating herbal skin treatment for psoriasis.

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We present an interesting case of salicylism arising from the use of methyl salicylate as part of a herbal skin cream for the treatment of psoriasis. A 40-year-old man became quite suddenly and acutely unwell after receiving treatment from an unregistered naturopath. Methyl salicylate (Oil of

Delayed Salicylate Toxicity in a 17-Year-Old Girl With Initially Undetectable Salicylate Concentration 3.9 Hours After Ingestion.

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We report the case of a 17-year-old girl with a 126-mg/kg nonenteric coated aspirin ingestion with nontoxic salicylate concentrations at 1.5 and 3.9 hours postingestion, who developed tinnitus and vomiting an estimated 8 hours postingestion, and who was subsequently found to have a toxic salicylate

A case of acute pancreatitis possibly associated with combined salicylate and simvastatin treatment.

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BACKGROUND Drug-induced acute pancreatitis is a rather rare clinical entity. From time to time, several cases have been reported in which statins or salicylates have been associated with the development of acute pancreatitis. There is only one report which implies the involvement of both drugs in

Reye's syndrome in a child on long-term salicylate medication.

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A case of Reye's syndrome in a four-year-old child on long-term salicylate medication for rheumatoid arthritis is reported. Severe fatty changes of the liver, lipid vacuolation in the renal proximal tubules, and severe brain oedema were the prominent postmortem findings. Symptoms of a trivial

Salicylate poisoning from enteric-coated aspirin. Delayed absorption may complicate management.

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Acute salicylate poisoning with enteric-coated aspirin may result from accidental ingestion, a suicide attempt, or a complication of long-term therapy. Because absorption of enteric-coated aspirin is delayed, use of the Done nomogram to determine toxicity may lead to underestimating the severity of

An unusual cause of interference in a salicylate assay caused by mitochondrial acetoacetyl-CoA thiolase deficiency.

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Mitochondrial acetoacetyl-CoA thiolase deficiency (or beta-ketothiolase deficiency) is a rare metabolic disorder characterized by acute episodes of severe acidosis and ketosis. A case is presented of an 18-month-old boy who presented with vomiting and diarrhoea and was found to be markedly acidotic.

Comparison of infusions of morphine and lysine acetyl salicylate for the relief of pain following thoracic surgery.

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A double-blind study comparing the effectiveness of a continuous infusion i.v. of lysine acetyl salicylate (LAS) with an infusion of morphine for the treatment of pain following pulmonary surgery is described. Mean pain scores in the two groups were not significantly different at any stage during

Comparison of infusions of morphine and lysine acetyl salicylate for the relief of pain after surgery.

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The effect of a constant i.v. infusion of lysine acetyl salicylate (LAS) on pain after operation was compared with that of a constant infusion of morphine in 30 patients undergoing unilateral inguinal herniorrhaphy. LAS provided analgesia equivalent to that provided by morphine and was associated

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