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salivary gland neoplasms/arginine
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TP53 single nucleotide polymorphism rs1042522 in salivary gland neoplasms.
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BACKGROUND
The TP53 single nucleotide polymorphism (SNP) rs1042522 encodes arginine (Arg) or proline (Pro). The Arg variant is more effective at inducing apoptosis than the Pro.
METHODS
We assessed this SNP through direct sequencing of benign and malignant salivary neoplasms of Brazilian patients
Amino acid utilization during cell growth and apoptosis induction.
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The amino acid utilization between human promyelocytic leukemia (HL-60), human oral squamous carcinoma (HSC-2, HSC-4, NA), human salivary gland tumor (HSG) and rat neuron cells (PC-12) were compared, using amino acid analyzer. All these cells consumed four essential amino acids (valine, methionine,
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