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salivary gland neoplasms/glutathione
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3 results
The expression of placental glutathione-s-transferase (gst-pi) in human normal salivary-glands and tumors.
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Immunohistochemical localization of placental glutathione S-transferase (GST-pi) in normal and inflammatory salivary glands (74 cases) and tumors (71 cases) was studied. In the normal and inflamed salivary glands of all locations (including major and minor salivary glands), the ductal epithelial
Over-expression of glutathione S-transferases, DT-diaphorase and an apparently tumour-specific cytosolic class-3 aldehyde dehydrogenase by Warthin tumours and mucoepidermoid carcinomas of the human parotid gland.
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Cytosolic class-3 aldehyde dehydrogenase (ALDH-3) may help to protect organisms from certain environmental aldehydes by catalysing their detoxification. Consistent with this notion are the reports that relatively high levels of this enzyme are present in tissues, e.g. stomach mucosa and lung, that
Effect of glutathione and N-acetylcysteine on hepatocellular modifications induced by 2-acetylaminofluorene.
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The exposure of rats to a dietary regimen containing 2-acetylaminofluorene induces a sequence of hepatocellular alterations leading to the development of preneoplastic nodules. Groups of 2-acetylaminofluorene-treated rats were given glutathione or N-acetylcysteine to evaluate the effects of these
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