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saponaria pumilio/dystonia

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Selective lesions of rabbit extraocular muscles injected with the anti-AChR immunotoxin saporin-mAb 73.

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OBJECTIVE To evaluate the effects on extraocular muscles of a skeletal muscle-specific immunotoxin, saporin-mAb 73, as an alternative to botulinum toxin to induce a permanent correction of oculo-facial dystonias or some forms of ocular motility disorders. METHODS An immunotoxin was prepared with a
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