schistosomiasis/dichloromethane

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Elevated levels of erythrocyte-conjugated dienes indicate increased lipid peroxidation in schistosomiasis mansoni patients.

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Schistosoma mansoni causes liver disease by inducing granulomatous inflammation. This favors formation of reactive oxygen species, including superoxide ions, hydrogen peroxide and hydroxyl radicals all of which may induce lipid peroxidation. We have evaluated lipid peroxidation in 18 patients with

Evaluation of the antibacterial and antidiarrhoeal activities of heeria insignis o. Ktze.

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Heeria insignis O. Ktze (Anacardiaceae) is an indigenous African shrub used in treatment of diarrhea, venereal diseases, tapeworm, hookworm, schistosomiasis, kidney trouble and for increasing lactation in women after childbirth. The methanol and dichloromethane extracts of the leaves were evaluated

Uncovering biological application of Brazilian green propolis: a phenotypic screening against Schistosoma mansoni

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The chemotherapy of schistosomiasis remains centered in the use of praziquantel. However, there has been growing resistant parasites to this drug. Thus, the aim of this work was to evaluate in vitro schistosomicidal activity of the hexanes-dichloromethane 1:1 extract of Brazilian green propolis

Praziquantel-Clays as Accelerated Release Systems to Enhance the Low Solubility of the Drug

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Praziquantel is an antiparasitic drug indicated for the treatment of the schistosomiasis disease. This drug has very low aqueous solubility, requiring high oral doses for its administration which gives rise to side effects, therapeutic noncompliance and the appearance of resistant forms of the

Anthelmintic activity in vitro and in vivo of Baccharis trimera (Less) DC against immature and adult worms of Schistosoma mansoni.

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Although its efficiency against all Schistosoma species, praziquantel (PZQ) shows low efficacy against schistosomula and juvenile stages. The potential for development of resistance to PZQ has justified the search for new alternative chemotherapies. In this scenario, studies to new formulations,

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