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sclerosis/hypoxia

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PCP receptor ligands and the use thereof

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FIELD OF THE INVENTION The invention is in the field of pharmaceutical compositions which are useful for the prevention and/or treatment of neurodegradation and other neuropathological conditions in animals. BACKGROUND OF THE INVENTION The amino acid L-glutamate is widely thought to act as a

PCP receptor ligands and the use thereof

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FIELD OF THE INVENTION The invention is in the field of pharmaceutical compositions which are useful for the prevention and/or treatment of neurodegradation and other neuropathological conditions in animals. BACKGROUND OF THE INVENTION The amino acid L-glutamate is widely thought to act as a

Crystalline forms of tricyclic compound acid salt or hydrate thereof, and method for making thereof

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TECHNICAL FIELD The present disclosure relates to novel crystalline acid salts of a tricyclic derivative or a hydrate thereof, and a production method thereof. BACKGROUND Drugs administered orally show medicinal effects through absorption, distribution, metabolism or elimination, and the intrinsic

Substituted 5-membered ring compounds and their use

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This application is a U.S. National Stage application of co-pending PCT application PCT/GB2004/002755, filed Jun. 24, 2004, which claims the priority of Great Britain Patent Application No. 0315111.5, filed Jun. 27, 2003. These applications are incorporated herein by reference in their

N,N'-disubstituted guanidines and their use as excitatory amino acid antagonists

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BACKGROUND OF THE INVENTION This invention relates to N,N'-disubstituted guanidine analogues, and to compounds and pharmaceutical compositions comprising the same, which possess neuroprotective capability. This invention further relates to methods for treating any disease of the nervous system in

N,N'-disubstituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention is in the field of medicinal chemistry. In particular, this invention relates to N,N'-disubstituted guanidine analogues, and to compounds and pharmaceutical composition comprising the same, which possess neuroprotective capability. This invention further relates

Tri-and tetra-substituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention relates to tri- and tetra-substituted guanidines, and to pharmaceutical compositions comprising the same, which possess neuroprotective capability. This invention further relates to methods involving the use of these compounds as excitatory amino acid

Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention relates to tri- and tetra-substituted guanidines, and to pharmaceutical compositions comprising the same, which possess neuroprotective capability. This invention further relates to methods involving the use of these compounds as excitatory amino acid

Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention relates to tri- and tetra-substituted guanidines, and to pharmaceutical compositions comprising the same, which possess neuroprotective capability. This invention further relates to methods involving the use of these compounds as excitatory amino acid

Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention relates to tri- and tetra-substituted guanidines, and to pharmaceutical compositions comprising the same, which possess neuroprotective capability. This invention further relates to methods involving the use of these compounds as excitatory amino acid

Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention relates to tri- and tetra-substituted guanidines, and to pharmaceutical compositions comprising the same, which possess neuroprotective capability. This invention further relates to methods involving the use of these compounds as excitatory amino acid

Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention relates to tri- and tetra-substituted guanidines, and to pharmaceutical compositions comprising the same, which possess neuroprotective capability. This invention further relates to methods involving the use of these compounds as excitatory amino acid

Tri-and tetra-substituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention relates to tri- and tetra-substituted guanidines, and to pharmaceutical compositions comprising the same, which possess neuroprotective capability. This invention further relates to methods involving the use of these compounds as excitatory amino acid

Branched adamantyl and noradamantyl aryl-and aralkylpiperazines with serotonin 5-HT1A activity

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This invention relates to novel branched adamantyl, noradamantyl aryl and aralkylpiperazines having serotonin 5-HT.sub.1A activity. More particularly, the present invention relates to compounds and methods using them to provide neuroprotection and prevent, inhibit or limit processes of

Branched adamantyl and noradamantyl aryl- and aralkylpiperazines with serotonin 5-HT1A activity

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This invention relates to novel branched adamantyl, noradamantyl aryl and aralkylpiperazines having serotonin 5-HT.sub.1A activity. More particularly, the present invention relates to compounds and methods using them to provide neuroprotection and prevent, inhibit or limit processes of
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