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scrub typhus/mirabilis

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Human anti-scrub typhus rickettsia and rabbit anti-Proteus antibodies recognize similar epitope in the O-polysaccharide part of Proteus mirabilis OXK lipopolysaccharide.

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In the Weil-Felix test, sera from patients infected with Orientia tsutsugamushi reacted with lipopolysaccharide (LPS) from Proteus mirabilis OXK strains. The O-polysaccharide of P. mirabilis OXK LPS consisted of pentasaccharide repeating units, with amidically-linked lysine residues. The lysine,

Structural and serological studies of the O-antigen of the bacterium Proteus mirabilis OXK (serogroup O3) used in the Weil-Felix test.

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Sugar analysis and 1H- and 13C-NMR spectroscopic studies showed that various strains of Proteus mirabilis OXK used as antigens in the Weil-Felix test for serodiagnosis of rickettsiosis (scrub typhus) produce lipopolysaccharides (LPSs) with the same O-specific polysaccharide chain having the
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