OBJECTIVE
To evaluate the feasibility of developing brain-targeted nasal delivery system of scutellarin by the passage between nase and brain in nasal olfactory area.
METHODS
The samples of cerebrospinal fluid (CSF) and blood were prepared by cranial puncture and femoral artery catheterization
OBJECTIVE
To observe the effect of Scutellarin (Scu) on expressions of nicotinic acetylcholine receptor (nAChR) subunit protein and mRNA in dementia rats, and to study its possible mechanism on dementia.
METHODS
Forty-two Wistar rats were randomly divided into 5 groups, i.e., the normal control
A capillary zone electrophoresis (CZE) method modified by β-cyclodextrin (β-CD) and acetonitrile (ACN) was developed for simultaneous determination of seven structurally similar flavonoids in Scutellariae Barbatae Herba (SBH) and its preparations. Molecular selectivity of the analytes by β-CD was in
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