secretin/inflammation

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Secretin dose-response in health and chronic pancreatic inflammatory disease.

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Stepwise increasing doses of secretin (0.078, 0.233, 0.7, and 2.1 U/kg-h) were given to 12 healthy volunteers (HV) and to patients with a history of chronic pancreatic inflammatory disease of more than five years (CP5, 12 patients) and two years or less (CP2, 9 patients). The maximal bicarbonate

The role of the secretin/secretin receptor axis in inflammatory cholangiocyte communication via extracellular vesicles.

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Small and large intrahepatic bile ducts consist of small and large cholangiocytes, respectively, and these cholangiocytes have different morphology and functions. The gastrointestinal peptide hormone, secretin (SCT) that binds to secretin receptor (SR), is a key mediator in cholangiocyte

Author Correction: The role of the secretin/secretin receptor axis in inflammatory cholangiocyte communication via extracellular vesicles.

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A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.

Proceedings: On the relationship between inflammatory joint disease and the foregut hormones, gastrin and secretin.

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IgE and IgD antibodies to cow milk and soy protein in duodenal fluid: effects of pancreozymin and secretin.

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Duodenal fluid IgE was reported to be increased in food allergy and in inflammatory conditions of the bowel. We studied the presence and specificity of IgE and IgD antibodies against alpha-casein, beta-lactoglobulin A, alpha-lactalbumin, bovine serum albumin and soy bean agglutinin using an

Gastrointestinal peptides in serum and synovial fluid from patients with inflammatory joint disease.

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The concentrations of immunoreactive vasoactive intestinal polypeptide (ir-VIP), immunoreactive pancreatic polypeptide (ir-PP), ir-somatostatin, and ir-secretin were measured in serum and synovial fluid from patients suffering from various inflammatory joint diseases. One group of patients were not

Signaling mechanisms of vasoactive intestinal peptide in inflammatory conditions.

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The vasoactive intestinal peptide (VIP) is a neuropeptide belonging to the secretin/glucagon family of peptides, which exerts a wide spectrum of immunological functions controlling the homeostasis of immune system through different receptors expressed in various immunocompetent cells. In the last

PACAP in immunity and inflammation.

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The pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide belonging to the VIP/secretin/glucagon family of peptides, produced by the lymphoid cells, which exerts a wide spectrum of immunological functions controlling the homeostasis of immune system through different receptors

Changes in gene expression of pancreatitis-associated protein and pancreatic secretory trypsin inhibitors in experimental pancreatitis produced by pancreatic duct occlusion in rats: comparison with gene expression of cholecystokinin and secretin.

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Pancreatic duct occlusion is known to produce a sustained increase in the plasma cholecystokinin (CCK) concentration and to affect the tissue content of CCK in the rat. The tissue content of CCK is correlated with regenerative changes in the pancreas after pancreatic duct occlusion. In the present

Secretin-stimulated MR cholangio-pancreatography in the evaluation of asymptomatic patients with non-specific pancreatic hyperenzymemia.

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OBJECTIVE To assess the diagnostic value of secretin-stimulated MRCP (SS-MRCP) compared with conventional MRCP in asymptomatic patients with mild elevations of pancreatic enzymes. METHODS Eighty asymptomatic patients with pancreatic hyperenzymemia underwent MR imaging at 1.5T-device (Signa EXCITE,

Effect of secretin and cholecystokinin-pancreozymin on plasma CEA concentration in patients with pancreatic carcinoma and pancreatitis.

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Plasma CEA concentration before and after administration of secretin and cholecystokinin-pancreozymin has been determined in 89 patients with neoplastic or inflammatory pancreatric disease and other neoplastic and nonneoplastic disorders. The purpose of the study was to expore the specificity and

Loss of secretin results in systemic and pulmonary hypertension with cardiopulmonary pathologies in mice.

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More than 1 billion people globally are suffering from hypertension, which is a long-term incurable medical condition that can further lead to dangerous complications and death if left untreated. In earlier studies, the brain-gut peptide secretin (SCT) was found to be able to control blood pressure

EUS and K-ras analysis of pure pancreatic juice collected via a duodenoscope after secretin stimulation for diagnosis of pancreatic mass lesion: a prospective study.

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BACKGROUND The early diagnosis of pancreatic cancer remains problematic. This prospective study assessed the utility of a combination of endoscopic ultrasound (EUS) and genetic analysis of pure pancreatic juice in the diagnosis of pancreatic mass lesions. METHODS One hundred seventy-six patients

[The influence of obstructive jaundice on wound healing of pancreatico-jejunostomy with reference to the function of the pancreas as assessed by glucose tolerance and pancreozymin-secretin test].

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Mongrel dogs jaundiced by ligation of the common bile duct for 3-week period were submitted to simultaneous biliary drainage and pancreatico-jejunostomy and sacrificed on day 1, 3, 5, 7, 14 and 30 after operation. The wound healing process of the anastomotic site was evaluated in terms of

Pancreatic duct abnormalities and pancreatic function in patients with chronic inflammatory bowel disease.

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BACKGROUND We performed a cross-sectional study to estimate the prevalence of duct abnormalities and exocrine pancreatic dysfunction in an unselected group of patients with inflammatory bowel disease (IBD) and to correlated the findings with clinical, endoscopic, and histologic variables. METHODS A

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