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secretin/seizures

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Lack of effect of secretin on kindling and seizures.

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Secretin infused into rats activates neurons located in brain areas controlling autonomic function and emotion. The brain activity of secretin is mediated, at least in part, through vagal pathways. It is known that afferent stimulation of the vagus nerve results in considerable antiepileptic

[Effects of lidocaine upon CCK-PZ and secretin producing paraneurons in the canine duodenum responding to luminal chemical stimuli (author's transl)].

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Amino acid solution (50 mM tryptophan and 50 mM phenylalanine in saline) introduced into the canine duodenal loop causes an increased enzyme output from the pancreas, whereas administration of 0.1 N HCl into the duodenal loop causes an increased juice flow from the organ. Local anesthetic,
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