sennoside a/atrophy

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Ultrastructure of mouse intestinal mucosa and changes observed after long term anthraquinone administration.

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In an attempt to study the relative toxicity of anthraquinonic laxatives on intestinal mucosa, we compared in mice the effects of fruit pulp containing sennosides A and B with those of a free anthraquinone, 1-8 dihydroxyanthraquinone. Observations have been made with transmission electron microscopy

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