sophocarpine/edema

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Anti-nociceptive and anti-inflammatory activity of sophocarpine.

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OBJECTIVE This study aimed to assess the anti-nociceptive and anti-inflammatory activity of sophocarpine in rodents. METHODS The anti-nociceptive effect was evaluated in two experimental animal models and anti-inflammatory effect in three animal models, and sophocarpine was given by tail vein

Protective effect of sophocarpine on lipopolysaccharide-induced acute lung injury in mice.

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Sophocarpine (SOP) is a tetracyclic quinolizidine alkaloid isolated from Sophora alopecuroides L. A number of studies have shown that SOP has anti-inflammatory actions and protects against a variety of tissue and organ injuries. The purpose of this study was to investigate the protective effects of

Sophocarpine administration preserves myocardial function from ischemia-reperfusion in rats via NF-κB inactivation.

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BACKGROUND Sophora alopecuroides L. (the clinical usefulness of compound Kudouzi injection) has been used mainly for the treatment of fever, inflammation, edema and pain. Sophocarpine, a tetracyclic quinolizidine alkaloid, is one of the most abundant active ingredients in Sophora alopecuroides L.

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