The effects of sophoramine on experimental arrhythmias in animals and its mechanisms were studied. Sopaoramine is an alkaloid isolated from Sophora alopecuroides L. The iv and ip LD50 of sophoramine in mice were found to be 74.90 +/- 17.86 and 106.15 +/- 1.05 mg/kg respectively. Sophoramine showed
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