spider bites/protease

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An examination of the potential role of spider digestive proteases as a causative factor in spider bite necrosis.

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Tissue necrosis following spider bites is a widespread problem. In the continental United States, the brown recluse (Loxosceles reclusa), hobo spider (Tegenaria agrestis), garden spider (Argiope aurantia) and Chiracanthium species, among others, reportedly cause such lesions. The exact mechanism

Highlights in the knowledge of brown spider toxins.

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Brown spiders are venomous arthropods that use their venom for predation and defense. In humans, bites of these animals provoke injuries including dermonecrosis with gravitational spread of lesions, hematological abnormalities and impaired renal function. The signs and symptoms observed following a

Biotechnological applications of brown spider (Loxosceles genus) venom toxins.

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Loxoscelism (the term used to define accidents by the bite of brown spiders) has been reported worldwide. Clinical manifestations following brown spider bites are frequently associated with skin degeneration, a massive inflammatory response at the injured region, intravascular hemolysis, platelet

Effect of brown spider venom on basement membrane structures.

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Loxoscelism or necrotic arachnidism are terms used to describe lesions and reactions induced by bites (envenomation) from spiders of the genus Loxosceles. Envenomation has been reported to provoke dermonecrosis and haemorrhage at the bite site and haemolysis, disseminated intravascular coagulation

Extracellular matrix molecules as targets for brown spider venom toxins.

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Loxoscelism, the term used to describe lesions and clinical manifestations induced by brown spider's venom (Loxosceles genus), has attracted much attention over the last years. Brown spider bites have been reported to cause a local and acute inflammatory reaction that may evolve to dermonecrosis (a

Comparison of enzymatic activity from three species of necrotising arachnids in Australia: Loxosceles rufescens, Badumna insignis and Lampona cylindrata.

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Necrotising arachnidism, or skin ulceration due to spider bite, is an unresolved clinical problem in Australia, with both the spiders responsible and disease pathogenesis remaining unclear. We have examined and compared enzymic activity from three species of Australian spiders capable of causing

Recent advances in the understanding of brown spider venoms: From the biology of spiders to the molecular mechanisms of toxins.

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The Loxosceles genus spiders (the brown spiders) are encountered in all the continents, and the clinical manifestations following spider bites include skin necrosis with gravitational lesion spreading and occasional systemic manifestations, such as intravascular hemolysis, thrombocytopenia and acute

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