Phytochemical investigation of the ethanol extract from the roots of Spiraea salicifolia L. (Rosaceae) led to the isolation of one new neolignan glycoside, (7S,8R)-3,5-dimethoxy-4',7-epoxy-8,5'-neolignan-3',4,9,9'-tetraol 9-O-α-L-rhamnopyranoside (1), along with two known neolignan glycosides,
Spiraea prunifolia var. simpliciflora (SP) is traditionally used as an herbal remedy to treat fever, malaria, and emesis. This study aimed to evaluate the anti-oxidative and anti-inflammatory properties of the methanol extract of SP leaves in tumor necrosis factor (TNF)-α-stimulated
Spiramine C-D, the atisine-type diterpenoid alkaloids isolated from the Chinese herbal medicine Spiraea japonica complex, are shown to have anti-inflammatory effects in vitro. In this study, we report that spiramine derivatives of spiramine C-D bearing α,β-unsaturated ketone induce apoptosis of
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