spondylarthropathies/nicotine

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Plasma levels of pentraxin 3 in patients with spondyloarthritis.

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BACKGROUND Determining the disease's inflammatory activity in spondyloarthritis (SpA) is difficult although very important as it is this that drives treatment. OBJECTIVE To investigate if plasma pentraxin-3 (PTX3) could act as an inflammatory marker in SpA. METHODS Eighty one SpA patients (11 with

Role of HLA-B27 in the comorbidities observed in Axial Spondyloarthritis: data from COMOSPA.

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To analyze the potential association between the presence of HLA-B27 and the different comorbidities observed in Axial Spondyloarthritis patients.A comparative cross-sectional study including Axial Spondyloarthritis patients from COMOSPA registry. COMOSPA

[Demonstration of subclinical pulmonary alveolitis in spondylarthropathies].

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Restrictive ventilatory dysfunction, lowered diffusing capacity, and apical fibrosis have been reported in ankylosing spondylitis. To investigate the pathogenesis of these abnormalities, we studied distal airspace cytology by performing bronchoalveolar lavage in 34 spondyloarthropathy patients

Influence of smoking and obesity on treatment response in patients with axial spondyloarthritis: a systematic literature review

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To assess whether smoking and obesity are predictors of poor treatment response in patients with axial spondyloarthritis (axSpA). A systematic literature review was performed by searching in MEDLINE and EMBASE up to June 2019 with a strategy based on the PICO approach: Population: patients with

Determining factors related to poor quality of life in patients with axial spondyloarthritis: results from the British Society for Rheumatology Biologics Register (BSRBR-AS).

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To determine modifiable factors associated with poor quality of life (QoL) in patients with axial spondyloarthritis (axSpA).Analysis of data from the British Society for Rheumatology Biologics Register in Ankylosing Spondylitis (BSRBR-AS) and validation of

Smoking in spondyloarthritis: unravelling the complexities.

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Tobacco smoking is a major threat to health. There is no doubt about the need to promote and support cessation at every opportunity. Smoking has a clear role in RA, but what evidence is there that the same relationship exists in SpA? In this review, we examine (the less cited) paradoxes and

Smoking cessation intervention for reducing disease activity in chronic autoimmune inflammatory joint diseases.

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Chronic inflammatory joint diseases (IJDs) affect 1% to 2% of the population in developed countries. IJDs include rheumatoid arthritis (RA), ankylosing spondylitis (AS), psoriatic arthritis (PsA), and other forms of spondyloarthritis (SpA). Tobacco smoking is considered a significant

[Alpha-1-antitrypsin deficiency in chronic inflammatory rheumatism and mechanical arthropathies. Preliminary results].

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Alpha-1-antitrypsine (AAT) plasmatic level is higher (p less than 0.01) in 85 chronic inflammatory arthropathies than in 238 non inflammatory arthropathies (2.5+/0.7 versus 2.1+/0.4 g/l). Among 15 rheumatoid arthritis (RA) with evaluated phenotype, alleles M2 are less frequent and M3 more frequent

Mannose-binding lectin (MBL) deficiency and tuberculosis infection in patients with ankylosing spondylitis.

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Ankylosing spondylitis (AS) patients may have higher prevalence of mannose-binding lectin (MBL) deficiency than normal individuals. MBL deficiency may influence susceptibility to infections. The aim of the study was to verify if MBL deficiency in patients with AS predisposes to infections. We

Recommendations for the management of comorbidity in hidradenitis suppurativa.

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BACKGROUND The association between hidradenitis suppurativa (HS) and some diseases is becoming relevant in recent years. Providing appropriate management of HS from an early stage requires to include prompt diagnosis and treatment of concomitant diseases and to prevent any potential comorbidity.

European S1 guideline for the treatment of hidradenitis suppurativa/acne inversa.

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Hidradenitis suppurativa/acne inversa (HS) is a chronic, inflammatory, recurrent, debilitating skin disease of the hair follicle that usually presents after puberty with painful, deep-seated, inflamed lesions in the apocrine gland-bearing areas of the body, most commonly the axillae, inguinal and

Air pollution in autoimmune rheumatic diseases: a review.

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Air pollution consists of a heterogeneous mixture of gasses and particles that include carbon monoxide, nitrates, sulfur dioxide, ozone, lead, toxic by-product of tobacco smoke and particulate matter. Oxidative stress and inflammation induced by inhaled pollutants may result in acute and chronic

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