OBJECTIVE
To determine whether the naturally occurring Thomsen-Friedenreich (TF) antigen-specific antibodies differ in avidity between cancer patients and controls to find a novel biomarker for stomach cancer.
METHODS
Serum samples were taken from patients with cancer and controls. The level of
OBJECTIVE
To identify a new tumor-associated antigen, a monoclonal antibody, SC142, was produced by immunizing mice with a stomach cancer cell line. The tumor specificity of mAb SC142 was studied by immunohistochemical staining, and the biochemical characteristics of this new gastrointestinal
OBJECTIVE
To study whether alterations in the glycosylation of immunoglobulin G (IgG) specific to the Thomsen-Friedenreich glycotope (TF) have diagnostic and prognostic potential in gastric cancer.
METHODS
Serum samples were obtained from patients with histologically verified gastric carcinoma (n =
OBJECTIVE
To study whether alterations in the sialylation of antibodies (Ab) specific to the Thomsen-Friedenreich (TF) glycotope have a diagnostic and prognostic potential in gastric cancer.
METHODS
Serum samples were taken from patients with gastric carcinoma (n = 142) and controls (n = 61). The
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