strychnos vanprukii/serotonin

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Hypotensive and spasmolytic effects of normacusine B from Strychnos atlantica root.

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Normacusine B, a tertiary indole alkaloid, was isolated in pure form from the root bark of Strychnos atlantica Krukoff & Barneby. In conscious unrestrained rats, normacusine B (1 mg/kg) decreased the mean arterial blood pressure (27.6 ± 8.4 mmHg, n = 6), followed by a significant increase in heart

Pharmacological characterisation of strychnine and brucine analogues at glycine and alpha7 nicotinic acetylcholine receptors.

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Strychnine and brucine from the plant Strychnos nux vomica have been shown to have interesting pharmacological effects on several neurotransmitter receptors, including some members of the superfamily of ligand-gated ion channels. In this study, we have characterised the pharmacological properties of

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