swertianolin/swertia mussotii

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The hepatoprotective effect and chemical constituents of total iridoids and xanthones extracted from Swertia mussotii Franch.

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BACKGROUND Total iridoids and xanthones (TIXS) were extracted from Swertia mussotii Franch, one of the most important eight Tibetan medicines in China, which was recorded in the book of Jingzhu Bencao and used for clinical treatment of cholestatic hepatitis for many years. Our aim was to study the

Determination of swertianolin in rat plasma by LC-MS/MS and its application to a pharmacokinetic study.

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A sensitive and rapid LC-MS/MS method has been developed and validated for quantifying swertianolin in rat plasma using rutin as an internal standard (IS). Following liquid-liquid extraction with ethyl acetate, chromatographic separation for swertianolin was achieved on a C18 column with a gradient

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