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tapinanthus/malaria
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3 results
Ex vivo and in vivo investigations of the effects of extracts of Vernonia amygdalina, Carica papaya and Tapinanthus sessilifolius on digoxin transport and pharmacokinetics: assessing the significance on rat intestinal P-glycoprotein efflux.
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Vernonia amygdalina (VA), Carica papaya (CP), and Tapinanthus sessilifolius (ML) are widely used in some countries as medicinal herbs to treat ailments including malaria, cancer, and diabetes. We previously reported the inhibitory effects of these herbs on permeability glycoprotein (P-gp) in Caco-2
P-glycoprotein mediated efflux in Caco-2 cell monolayers: the influence of herbals on digoxin transport.
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BACKGROUND
Several herbal medicines are concomitantly used with conventional medicines with a resultant increase in the recognition of herb-drug interactions. The phytomedicines Vernonia amygdalina Delile (VA), family Asteraceae; Azadiractha indica A. Juss (NL), family Meliaceae; Morinda lucida
In vitro and in vivo antimalarial studies of Striga hermonthica and Tapinanthus sessilifolius extracts.
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The antimalarial activities of the methanol extracts of Striga hermonthica (whole plant) and Tapinanthus sessilifolius (leaves), commonly used in Northern Nigeria for the treatment of malaria, were evaluated. In the in vitro antiplasmodial analysis, the extracts of T. sessilifolius and S.
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