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taxol/breast neoplasms
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12 results
Taxol treatment of breast cancer
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FIELD OF THE INVENTION
The present invention relates to a method of treating patients who have breast cancer.
More particularly, the invention relates to treatment of patients with a taxol solution administered as a 96 hour continuous infusion every 21 days.
BACKGROUND OF THE INVENTION
Taxol is a
Method of preparing a taxol derivative
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BACKGROUND OF THE INVENTION
Taxol is a member of the taxane family of diterpenes, having the structure shown below: ##STR2##
The numbering system shown for taxol is that recommended by IUPAC (IUPAC, Commission on the Nomenclature of Organic Chemistry, 1978).
The chemistry of the potent anticancer
Transfer of taxol from yew tree cuttings into a culture medium over time
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BACKGROUND OF THE INVENTION
Cancer is one of the leading causes of death in our country today. Despite extensive research, a cure for cancer is not yet a reality. Taxol is known to be cytotoxic against numerous malignant tumors. The results of studies indicate that taxol has been effective against
3-(arylsulfonylamino)-tetrahydrofuran-3-carboxylic acid hydroxamides
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BACKGROUND OF THE INVENTION
The present invention relates to 3-(arylsulfonylamino)-tetrahydrofuran-3-carboxylic acid hydroxamide derivatives, and to pharmaceutical compositions and methods of treatment of inflammation, cancer and other disorders.
The compounds of the present invention are inhibitors
Compositions, methods and kits relating to HER-2 cleavage
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FIELD OF THE INVENTION
The present invention relates to compositions, methods and kits based on the ADAM-mediated cleavage of Her-2. The present invention also relates to treatments for cancer, and in particular, breast cancer, by modulating the ADAM-mediated cleavage of Her-2. Further, the
Compositions, methods and kits relating to Her-2 cleavage
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FIELD OF THE INVENTION
The present invention relates to compositions, methods and kits based on the ADAM-mediated cleavage of Her-2. The present invention also relates to treatments for cancer, and in particular, breast cancer, by modulating the ADAM-mediated cleavage of Her-2. Further, the
Pharmaceutical preparations and methods for inhibiting tumors
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FIELD OF THE INVENTION
The present invention relates to pharmaceutical preparations (i.e., composition) for use as tumor suppressive agents for tumors arising from cancers such as prostatic adenocarcinoma, stomach cancer, breast cancer, endometrial and ovarian cancers, and benign prostate
Pharmaceutical preparations and methods for inhibiting tumors
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FIELD OF THE INVENTION
The present invention relates to pharmaceutical preparations (i.e., composition) for use as tumor suppressive agents for tumors arising from cancers such as prostatic adenocarcinoma, stomach cancer, breast cancer, endometrial and ovarian cancers, and benign prostate
Pharmaceutical preparations and methods for inhibiting tumors
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FIELD OF THE INVENTION
The present invention relates to pharmaceutical preparations (i.e., composition) for use as tumor suppressive agents for tumors arising from cancers such as prostatic adenocarcinoma, stomach cancer, breast cancer, endometrial and ovarian cancers, and benign prostate
Synthesis of (1)-beta-elemene, (-)-beta-elemenal, (-)-beta-elemenol, (-)-beta-elemene fluoride and their analogues, intermediates, and composition and uses thereof
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DESCRIPTION
1. Field of the Invention
The present invention is in the field of elemene analogs and elemenal analogues. In particular, the present invention relates to processes for the preparation of (-)-beta-elemene, (-)-beta-elemenal (a (-)-beta-elemene metabolite in mammals), (-)-beta-elemenol,
Synergistic effects of nuclear transcription factor NF-.kappa.B inhibitors and anti-neoplastic agents
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the field of cancer treatment. More specifically, the present invention relates to the unexpected synergistic effects of nuclear transcription factor NF-.kappa.B inhibitors and anti-neoplastic agents in
Synergistic compositions consisting essentially of combinations of active agents selected from oridonin, wogonin, and isoliquiritigenin for the prevention of neoplasia
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RELATED APPLICATIONS
This application is the U.S. National Phase of International Application No. PCT/GB2007/001720, filed 10 May 2007, published in English, which application claims priority under 35 U.S.C. .sctn.119 or 365 to Great Britain Application No. 0609386.8, filed 11 May 2006. The entire
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