terpene/obesity

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Human TRPA1 activation by terpenes derived from the essential oil of daidai, Citrus aurantium L. var. daidai Makino.

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Daidai (bitter orange, Citrus aurantium) is characterized by its fresh citrus scent. In Japanese cuisine, its juice is an important ingredient. As tons of industrial waste is obtained while processing the daidai juice, additional utilization of this waste has great social value. In our study,

Pancreatic lipase inhibition activity of trilactone terpenes of Ginkgo biloba.

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The prevalence of obesity is increasing at an alarming rate, but, unfortunately, only a few drugs are currently available on the market. In the present study, the methanolic extract of Ginkgo biloba L. (Ginkgoaceae) was investigated as an inhibitor of pancreatic lipase (PL) in an attempt to explain

Inhibition of key enzymes linked to obesity by preparations from Mediterranean dietary plants: effects on α-amylase and pancreatic lipase activities.

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One of the most important strategy in the treatment of obesity includes the development of nutrient digestion and absorption inhibitors. Inhibition of digestive enzymes is one of the most widely studied mechanisms used to determine the potential efficacy of natural products as hypolipidemic and

Traditional uses, phytochemistry and pharmacological activities of the genus Cinnamomum (Lauraceae): A review

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Species of Cinnamomum exhibit excellent economic and medicinal value, and have found use in traditional medicine, are consumed as a spice, as well as being cultivated as landscape plants. Investigations into the pharmacological activities of the genus Cinnamomum revealed that it manifested a wide

In vitro anti-HIV and antioxidant activity of Hoodia gordonii (Apocynaceae), a commercial plant product.

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BACKGROUND Hoodia gordonii products are widely commercialized for anti-obesity purposes; however, minimal research is available on the other health properties demonstrated by this popular herbal plant. METHODS H. gordonii crude extracts (ethanol and ethyl acetate) were assayed for in vitro

Cembrane diterpenoids from the soft coral Sarcophyton trocheliophorum Marenzeller as a new class of PTP1B inhibitors.

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A detailed investigation of the South China Sea soft coral Sarcophyton trocheliophorum Marenzeller yielded, along with six known terpenes (6-11), the new sarcophytonolides N-R (1-5), whose structures have been elucidated by detailed spectroscopic analysis. Sarcophytonolides N-R are mono- or bicyclic

Therapeutic Strategies of Plant-derived Compounds for Diabetes Via Regulation of Monocyte Chemoattractant Protein-1.

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BACKGROUND Monocyte chemoattractant protein-1 (MCP-1) is a member of the CC chemokine family that plays a key role in the inflammatory process. It has been broadly studied in the aspect of its role in obesity and diabetes related diseases. MCP-1 causes the infiltration of macrophages into obese

Influence of nutrients and other dietary materials on cytochrome P-450 enzymes.

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The cytochrome P-450 (P-450) enzymes are collectively responsible for the bulk of oxidation of xenobiotic chemicals, including drugs, pesticides, and carcinogens. This biotransformation can result in either increased or decreased toxicity, depending on the situation. The regulation of individual

Effect of body condition on consumption of pine needles (Pinus ponderosa) by beef cows.

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We determined whether cows in low (LBC) or high body condition (HBC) would consume different amounts of green pine needles (Pinus ponderosa). Cows (mature; open Hereford and Hereford x Angus) were fed a maintenance basal diet (alfalfa pellets) for Exp. 1 and 2; during Exp. 3 and 4, cows were fed

Lobularia maritima (L.) Desv. Aerial Parts Methanolic Extract: In Vitro Screening of Biological Activity.

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Lobularia maritima (L.) Desv. is a perennial herb growing wild in the Mediterranean basin. The aim of this work was to assess the fatty acid, terpene, phytosterol, and phenolic composition of the methanolic extract and its sub-fractions using Gas Chromatography-Mass Spectrometry (GC-MS),

Chemical Components and Biological Activities of the Genus Phyllanthus: A Review of the Recent Literature.

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Medicinal plants have served humans since prehistoric times to treat various ailments. Both developed and underdeveloped countries rely on traditional systems of medication using natural sources from plants. Phyllanthus is one of the largest genus in the family Phyllanthaceae, comprising over 700

Nutritional approaches to prevention and treatment of gallstones.

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Cholesterol gallstones are among the most common gastrointestinal disorders in Western societies. Individuals with gallstones may experience various gastrointestinal symptoms and are also at risk of developing acute or chronic cholecystitis. Cholecystectomy is the most frequently recommended

Phytochemicals as modifiers of gut microbial communities

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A healthy gut microbiota (GM) is paramount for a healthy lifestyle. Alterations of the GM have been involved in the aetiology of several chronic diseases, including obesity and type 2 diabetes, as well as cardiovascular and neurodegenerative diseases. In pathological conditions, the diversity of the

Phytochemical constituents, biological activities, and health-promoting effects of the genus Origanum

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Origanum species are mostly distributed around the Mediterranean, Euro-Siberian, and Iran-Siberian regions. Since time immemorial, the genus has popularly been used in Southern Europe, as well as on the American continent as a spice now known all over the world under the name "oregano" or

Quassinoids in Brucea javanica are potent stimulators of lipolysis in adipocytes.

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Obesity is associated with a number of metabolic disorders. Lipolysis is the initial step in the metabolism of lipids stored in adipocytes and is therefore considered a therapeutic target for obesity. Quassinoids are unique terpenes found in plants of the Simaroubaceae family, which were recently

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