We describe a Chinese family among whom five members in three generations had a flat umbilicus with vertical and male to male transmission indicative of autosomal dominant inheritance. Except the proband, who also had Tetralogy of Fallot, other affected members had a flat umbilicus as an isolated
Two brothers, age 16 months and 3 years, had a seemingly unique combination of hydrocephalus of the lateral ventricles and a low-insertion umbilicus. Both had similar mildly unusual facies and inguinal hernias; one had unilateral cryptorchidism. The older brother had tetralogy of Fallot, and the
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