thrombocytopenia/nicotine

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Thrombocytopenia as a thrombotic risk factor in patients with antiphospholipid antibodies without disease criteria.

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BACKGROUND The antiphospholipid syndrome (APS) is an acquired immune disorder defined by the presence of thrombosis (arterial and/or venous) and/or pregnancy morbidity along with the presence of positive antiphospholipid antibodies (aPL). There is a clear relationship between aPL and some events not

Outcomes in an obstetrical population with hereditary thrombophilia and high tobacco use.

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OBJECTIVE The purpose of this study was to examine birth outcomes in women treated or untreated for thrombophilia during pregnancies affected or not by tobacco exposure. METHODS This was a retrospective cohort study of consecutive women from a single maternal fetal medicine clinic who delivered

Recurrent venous thrombosis following free flap surgery: The role of heparin-induced thrombocytopenia.

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Complications following free tissue transfer have been well established in the literature. Common and rare causes of free flap failure must be addressed by the treating surgeon when microvascular patency is threatened. With the evolution and prevalence of microsurgery, 'rare' causes of free flap

[The incidence and risk factors for thrombosis in primary immune thrombocytopenia].

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Objective: To probe the incidence and risk factors for thrombosis in Chinese immune thrombocytopenia through a retrospective analysis of the inpatients referred to the Blood Disease Hospital, CAMS & PUMC. Methods: A retrospective survey of 3 225 patients with ITP from October 2005 to December 2017

Cerebrovascular ischemic events with high positive anticardiolipin antibodies.

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OBJECTIVE The aim of our study was to characterize the patient profile and prognostic value associated with high positive IgG (>100 GPL) anticardiolipin antibodies (aCL). METHODS We studied the clinical, laboratory, radiological, and prospective historical features of ischemic cerebrovascular

PP170. Prenatal vitamin C and E supplementation is associated with a reduction in placental abruption and preterm birth in smokers.

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BACKGROUND Maternal tobacco use increases the incidence of numerous adverse pregnancy outcomes including miscarriage, small for gestational age infants, spontaneous preterm birth and placental abruption. OBJECTIVE We evaluated the relationship between prenatal vitamin C/E supplementation and

Association of Obstetric and Neonatal Outcomes With Deviation From Guidelines for Gestational Carriers

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Objective: To evaluate whether deviation from American Society for Reproductive Medicine (ASRM) safety guidelines for women who are gestational carriers is associated with increased risk of severe obstetric and perinatal morbidity and

A phase I study of cabazitaxel in combination with platinum and 5-fluorouracil (PF) in locally advanced squamous cell carcinoma of head and neck (LA-SCCHN).

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There is a clinical need to improve outcomes for patients with locally advanced squamous cell carcinoma of the head and neck (LA-SCCHN), especially in Human Papilloma Virus (HPV) negative and HPV positive subtypes with a significant history of tobacco use. In animal models bearing SCCHN, Cabazitaxel

Cases from the Osler Medical Service at Johns Hopkins University.

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PRESENTING FEATURES: An 18-year-old white man was admitted to the Osler Medical Service with the chief complaint of back pain. Two weeks prior to admission, the patient developed diffuse and aching upper back pain. Over the next couple of days, he also developed severe anterior chest pain that was

Yield and costs of screening growth-retarded infants for torch infections.

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Many infants with intrauterine growth retardation (IUGR) are screened for TORCH infections. The yield and costs of such a practice may not be justifiable. Medical charts of infants with IUGR who had a workup for toxoplasmosis, other (infections), rubella, cytomegalovirus (infection), and herpes

Gastric leishmaniasis in the setting of HIV/AIDS infection at Community Hospital in Southeastern United States

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Introduction: Visceral leishmaniasis, caused by the Leishmania donovani complex, is responsible for over 20 000 deaths per year. This disease often affects the immunocompromised with an increased prevalence in those with human

Hepatitis C virus related cirrhosis: time to occurrence of hepatocellular carcinoma and death.

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BACKGROUND In patients with hepatitis C virus (HCV) infection and cirrhosis, long term outcome and the incidence of hepatocellular carcinoma (HCC) are still debated. METHODS From January 1987 to January 1997, 416 patients (240 male, median age 57 years) with uncomplicated Child-Pugh A HCV related

Hemophagocytic lymphohistiocytosis complicated by polyserositis: A case report.

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Hemophagocytic lymphohistiocytosis (HLH) is a rare group of disorders of immune dysregulation characterized by clinical symptoms of severe inflammation. There are basically two types of clinical scenarios: Familial HLH and sporadic HLH. It is thought that the syndrome is implicated in

Levamisole/Cocaine Induced Systemic Vasculitis and Immune Complex Glomerulonephritis.

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Levamisole is an antihelminthic and immunomodulator medication that was banned by the USFDA in 1998. It has been increasingly used to adulterate cocaine due to its psychotropic effects and morphological properties. Adverse reactions including cutaneous vasculitis, thrombocytopenia, and

Inability to have children caused by recurrent HELLP syndrome in early pregnancies - implications for a review of literature.

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This review is inspired by a case of two pregnancies of the same patient complicated by HELLP syndrome, which suggests that there is a predisposition for the occurrence of preeclampsia and HELLP syndrome in early pregnancy. HELLP syndrome, uncommon below the 20th week and rarer still in two

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