thyroid dysgenesis/edema

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Sibs with the fetal akinesia sequence, fetal edema, and malformations: a new syndrome?

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Pena and Shokeir [J Pediatr 85:373-375. 1974] first described a syndrome characterized by multiple ankyloses, camptodactyly, facial anomalies, and pulmonary hypoplasia, which was later termed Pena-Shokeir I syndrome. Recent evidence suggests that a more accurate designation for this condition is the

Thyroid Adenoma and Ectopic Thyroid Carcinoma in a Guinea Pig (Cavia porcellus).

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A 56-mo-old male guinea pig (Cavia porcellus) presented with gradual weight loss from 757 to 691 g during the preceding month. Cardiac-specific diagnostics detected decreased cardiac contractility, moderate cardiomegaly, pericardial effusion, and pulmonary edema. At 1 mo after presentation, the

Congenital hypothyroidism in Taiwan: experience before mass screening.

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The clinical data of 91 patients with congenital hypothyroidism, not detected by neonatal screening, were reviewed. Our results disclosed that congenital hypothyroidism in Taiwan is more common in girls than boys, with a female to male ratio of 1.8:1. The majority of our patients were from a first

High prevalence of congenital hypothyroidism in the Greek Cypriot population: results of the neonatal screening program 1990-2000.

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OBJECTIVE To evaluate the results of the screening program for congenital hypothyroidism (CH) in the Greek Cypriot population. METHODS During 1990-2000, 109,532 neonates were screened by TSH determination. Permanent CH was proven with biochemical findings after discontinuation of treatment for

Early weaning PCB 95 exposure alters the neonatal endocrine system: thyroid adipokine dysfunction.

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Polychlorinated biphenyls (PCBs) are persistent environmental pollutants that can severely disrupt the endocrine system. In the present study, early-weaned male rats were administered a single dose of 2,3,6-2',5'-pentachlorinated biphenyl (PCB 95; 32 mg/kg per day, by i.p. injection) for two

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