thyroid dysgenesis/obesity

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Severe thyroid atrophy due to prolonged ingestion of thyroid hormone for treatment of obesity.

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Severe thyroid atrophy was found at the autopsy of a 39-year-old white woman who died of myocarditis, probably of viral etiology. Prolonged ingestion of thyroid hormone for the treatment of obesity appears to be the only plausible explanation for the atrophy, secondary to suppression of the

Two patients with chromosome 22q11.2 deletion presenting with childhood obesity and hyperphagia.

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Chromosome 22q11.2 deletion syndrome is a clinically heterogeneous condition of intellectual disability, parathyroid and thyroid hypoplasia, palatal abnormalities, cardiac malformations and psychiatric symptoms. Hyperphagia and childhood obesity is widely reported in Prader-Willi Syndrome (PWS) but

Thyroid Embryonic Anomalies Involving the Medial and Lateral Anlagen: Two Surgical Case Reports.

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An ectopic anomalous accessory thyroid is extremely rare. We present two related case reports.A 43-year-old morbidly obese female presented with a palpable left thyroid mass. Initial impression after preoperative workup was a diffuse bilateral multinodular

An Alport syndrome boy with Van Wyk-Grumbach syndrome induced by prolonged untreated congenital hypothyroidism

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Alport syndrome (AS) is a rare genetic disorder that causes progressive nephritis and is more common among males. Studies have reported an association between thyroid antibodies and hypothyroidism in patients with AS, but the relevance of this relationship is under debate. Prolonged untreated

Spontaneous primary hypothyroidism in 7 adult cats.

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BACKGROUND Naturally occurring hypothyroidism in adult cats is rare, with only 4 cases reported. OBJECTIVE To describe the historical, clinical, laboratory, and scintigraphic features of adult cats with spontaneous hypothyroidism. METHODS Seven adult cats referred for suspected

A case of primary hypothyroidism causing central nervous system atherosclerosis in a dog.

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A 2-year-old, castrated male, Australian shepherd was presented with a history of chronic mild ataxia, obesity, and lethargy. The dog was treated with levothyroxine, but the ataxia worsened. Cranial nerve abnormalities developed and the dog was euthanized. Postmortem examination revealed marked

Acquired von Willebrand's syndrome caused by primary hypothyroidism in a 5-year-old girl.

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Background Acquired von Willebrand's syndrome (aVWS) associated with hypothyroidism is rare in children and more often diagnosed during the peripubertal period in the context of Hashimoto's thyroiditis. Case presentation A 5-year-old girl was referred to the paediatric haematology unit for rectal

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