torilis/silica

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Torilin from Torilis japonica, as a new inhibitor of testosterone 5 alpha-reductase.

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The methanolic extract of the fruits of Torilis japonica showed a potent inhibition against 5 alpha-reductase activity in vitro. Bioassay-guided fractionation of the methanol extract of the fruits followed by repeated silica gel chromatography led to the isolation of an active principle and its

Guaiane sesquiterpenoids from Torilis japonica and their cytotoxic effects on human cancer cell lines.

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A new compound 2 and two known guaiane-type sesquiterpenoids were isolated from the methylene chloride-soluble fraction of the methanolic extract of the fruits of Torilis japonica (Umbelliferae) through repeated silica gel and Sephadex LH-20 column chromatography. Their chemical structures were

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